Gene Information gene info

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GENE：CNTFR

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CNTFR
FullNmae ciliary neurotrophic factor receptor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2170
EnsembleID ENSG00000122756
Uniprot P26992

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CNTFR immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CNTFR GO:0001967,GO:0003360,GO:0004896,GO:0004897,GO:0004897,GO:0005102,GO:0005515,GO:0005886,GO:0007165,GO:0007399,GO:0007548,GO:0008284,GO:0009897,GO:0016324,GO:0019898,GO:0019955,GO:0019955,GO:0043524,GO:0060538,GO:0070110,GO:0070110,GO:0070120,GO:0070120,GO:0097049,GO:0097059,GO:0097059,GO:2000672

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CNTFR hsa:1271 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
CNTFR hsa:1271 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CNTF CNTFR 10812968 23331499 7810882 8081242 8627290 stimulation N/A SignaLink
CNTFR JAK1 11464862 23331499 stimulation N/A SignaLink
CNTFR STAT4 10582086 23331499 stimulation N/A SignaLink
CNTFR STAT1 10582086 23331499 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
CRK CNTFR 20005715 interaction type N/A PSP,SignaLink
GRB2 CNTFR 20005715 interaction type N/A PSP,SignaLink
NCK1 CNTFR 20005715 interaction type N/A PSP,SignaLink

Source Target Pmid Interactiontype Methods Database
SMARCA4 CNTFR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CNTFR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CNTFR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CNTFR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CNTFR 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 CNTFR 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000019D79B CNTFR 23970374 25416803 mrna cleavage,inhibition western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
KRTAP4-12 CNTFR 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
CNTF CNTFR 10812968 14525934 18775332 24234451 25348397 7810882 8627290 physical association affinity chromatography technology,electron microscopy,experimental interaction detection,isothermal titration calorimetry,molecular sieving,physical interaction,in vivo ComPPI,HPRD,IntAct
CRK CNTFR 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
APPBP2 CNTFR 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
IL6ST CNTFR 11285233 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
NCK1 CNTFR 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
GRB2 CNTFR 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
PLSCR1 CNTFR 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
FYN CNTFR 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
CLCF1 CNTFR 10966616 11285233 11294841 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CRLF1 CNTFR 10966616 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
LIFR CNTFR 11285233 11943154 12707266 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
CNTFR JPT2 25348397 N/A physical interaction ComPPI
CNTFR ABL1 17474147 24234451 25348397 physical association peptide array ComPPI,IntAct
CNTFR CRAMP1 21900206 24234451 25348397 physical association two hybrid ComPPI,IntAct
TANK CNTFR 24234451 30561431 association virotrap IntAct
IL6ST CNTFR 11285233 12707266 15051883 27898060 N/A N/A OmniPath
LIFR CNTFR 11285233 11943154 12707266 15051883 27898060 N/A N/A OmniPath
CNTF CNTFR 10812968 10966616 27898060 7539796 7810882 8627290 stimulant N/A OmniPath
CNTFR CRLF1 10966616 27898060 N/A N/A OmniPath
CLCF1 CNTFR 10966616 11285233 11294841 27898060 stimulant N/A OmniPath
PNP CNTFR 15051883 27898060 N/A N/A OmniPath

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