Gene Information gene info

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GENE：ZCCHC8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ZCCHC8
FullNmae zinc finger CCHC-type containing 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25265
EnsembleID ENSG00000033030
Uniprot Q6NZY4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ZCCHC8 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ZCCHC8 GO:0000398,GO:0003723,GO:0003723,GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0008270,GO:0016076,GO:0016604,GO:0031499,GO:0034470,GO:0034470,GO:0071013,GO:0071013

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BMI1 ZCCHC8 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ESR1 ZCCHC8 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 ZCCHC8 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ZCCHC8 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 ZCCHC8 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ZCCHC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ZCCHC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ZCCHC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ZCCHC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ZCCHC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ZCCHC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ZCCHC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ZCCHC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ZCCHC8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ZCCHC8 N/A trascriptional regulation,stimulation inferred by curator TFlink
E2F2 ZCCHC8 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 ZCCHC8 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000075C1E1 ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 ZCCHC8 23313552 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000759B6A ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF ZCCHC8 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 ZCCHC8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 ZCCHC8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001B12A4 ZCCHC8 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001AFC71 ZCCHC8 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 ZCCHC8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF ZCCHC8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000224AEA ZCCHC8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 ZCCHC8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 ZCCHC8 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000259AE4 ZCCHC8 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PPP2R1A ZCCHC8 25361965 interaction type N/A PTMCode2
ZCCHC8 PPP2R1A 25361965 interaction type N/A PTMCode2
PPP2R2B ZCCHC8 25361965 interaction type N/A PTMCode2
ZCCHC8 PPP2R2B 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPP2R1A ZCCHC8 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
U2AF1L5 ZCCHC8 25348397 N/A physical interaction ComPPI
BMI1 ZCCHC8 25348397 N/A physical interaction ComPPI
EXOSC1 ZCCHC8 25348397 N/A physical interaction ComPPI
EXOSC8 ZCCHC8 25348397 N/A physical interaction ComPPI
USP7 ZCCHC8 25348397 N/A physical interaction ComPPI
INPPL1 ZCCHC8 25348397 N/A physical interaction ComPPI
U2AF2 ZCCHC8 25348397 N/A physical interaction ComPPI
CUL3 ZCCHC8 25348397 N/A physical interaction ComPPI
YWHAB ZCCHC8 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 ZCCHC8 25348397 N/A physical interaction ComPPI
PRPF40A ZCCHC8 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
RPA1 ZCCHC8 25348397 N/A physical interaction ComPPI
GBA ZCCHC8 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA1 ZCCHC8 25348397 N/A physical interaction ComPPI
CLK2 ZCCHC8 23602568 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
XPO1 ZCCHC8 25348397 N/A physical interaction ComPPI
RPA2 ZCCHC8 25348397 N/A physical interaction ComPPI
RPA3 ZCCHC8 25348397 N/A physical interaction ComPPI
THOC1 ZCCHC8 25348397 N/A physical interaction ComPPI
PSMC5 ZCCHC8 25348397 N/A physical interaction ComPPI
RET ZCCHC8 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SOX2 ZCCHC8 25348397 N/A physical interaction ComPPI
PSMC4 ZCCHC8 25348397 N/A physical interaction ComPPI
RNF2 ZCCHC8 25348397 N/A physical interaction ComPPI
DROSHA ZCCHC8 25348397 N/A physical interaction ComPPI
MTREX ZCCHC8 25348397 N/A physical interaction ComPPI
PPP2R2A ZCCHC8 24234451 25348397 28330616 association pull down,proximity-dependent biotin identification ComPPI,IntAct
MAP1LC3A ZCCHC8 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
SNCA ZCCHC8 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPF ZCCHC8 25348397 N/A physical interaction ComPPI
NCBP2 ZCCHC8 24234451 25348397 26382858 26496610 association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
C1D ZCCHC8 25348397 N/A physical interaction ComPPI
BRCA1 ZCCHC8 17525332 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOSC7 ZCCHC8 25348397 N/A physical interaction ComPPI
RBM11 ZCCHC8 25348397 N/A physical interaction ComPPI
RBM7 ZCCHC8 16263084 24234451 25348397 26186194 26344197 26496610 27898060 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
LUC7L ZCCHC8 25348397 N/A physical interaction ComPPI
CAT ZCCHC8 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EXOSC3 ZCCHC8 25348397 N/A physical interaction ComPPI
PSMD13 ZCCHC8 25348397 N/A physical interaction ComPPI
RBM4B ZCCHC8 25348397 N/A physical interaction ComPPI
TXNDC9 ZCCHC8 25348397 N/A physical interaction ComPPI
PSMC2 ZCCHC8 25348397 N/A physical interaction ComPPI
SIRT7 ZCCHC8 25348397 N/A physical interaction ComPPI
PPP2R2D ZCCHC8 24234451 25348397 28330616 association anti tag coimmunoprecipitation,pull down,physical interaction,proximity-dependent biotin identification ComPPI,IntAct
KSR1 ZCCHC8 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
USP28 ZCCHC8 25348397 N/A physical interaction ComPPI
ZCCHC8 PPP2R2B 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
ZCCHC8 APP 25348397 N/A physical interaction ComPPI
ZCCHC8 U2AF1 25348397 N/A physical interaction ComPPI
ZCCHC8 THOC6 25348397 N/A physical interaction ComPPI
ZCCHC8 MICB 25348397 N/A physical interaction ComPPI
ZCCHC8 ZC3H15 25348397 N/A physical interaction ComPPI
ZCCHC8 PSMB6 25348397 N/A physical interaction ComPPI
ZCCHC8 PPP2R2C 25348397 N/A physical interaction ComPPI
ZCCHC8 ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MKI67 ZCCHC8 24234451 26949251 association anti tag coimmunoprecipitation IntAct

Visualization










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