Gene Information gene info

GENE:MCUB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MCUB
FullNmae mitochondrial calcium uniporter dominant negative subunit beta
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26076
EnsembleID ENSG00000005059
Uniprot Q9NWR8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MCUB mpt 32299299 MCUb overexpressing mice demonstrated inhibited mitochondrial Ca2+ uptake in cardiomyocytes and partial protection from ischemia-reperfusion injury by reducing mitochondrial permeability transition pore opening. retulator signature
MCUB immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MCUB GO:0005654,GO:0005739,GO:0005739,GO:0005743,GO:0005743,GO:0005743,GO:0006851,GO:0016020,GO:0019855,GO:0019855,GO:0034704,GO:0036444,GO:0036444,GO:0043231,GO:0051560,GO:0051560,GO:0051560,GO:1990246,GO:1990246,GO:1990246

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MCUB 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C MCUB 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MCUB 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MCUB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MCUB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MCUB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MCUB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MCUB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MCUB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MCUB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MCUB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MCUB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 MCUB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MCUB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 MCUB 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000005481D MCUB 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SETDB1 MCUB 25348397 N/A physical interaction ComPPI
ZBTB16 MCUB 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GNAI2 MCUB 25348397 N/A physical interaction ComPPI
ASPH MCUB 25348397 N/A physical interaction ComPPI
FAF2 MCUB 25348397 N/A physical interaction ComPPI
SLC25A10 MCUB 25348397 N/A physical interaction ComPPI
MRPL12 MCUB 25348397 N/A physical interaction ComPPI

Visualization