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GENE：GEMIN6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GEMIN6
FullNmae gem nuclear organelle associated protein 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20044
EnsembleID ENSG00000152147
Uniprot Q8WXD5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GEMIN6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GEMIN6 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GEMIN6 GO:0000245,GO:0000387,GO:0000387,GO:0000387,GO:0000387,GO:0000398,GO:0003723,GO:0005515,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0016604,GO:0032797,GO:0032797,GO:0032797,GO:0034719,GO:0097504

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 GEMIN6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 GEMIN6 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GEMIN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GEMIN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GEMIN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GEMIN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GEMIN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GEMIN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 GEMIN6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000D5659 GEMIN6 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A GEMIN6 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD02D GEMIN6 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000C4DB5 GEMIN6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 GEMIN6 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000077AED GEMIN6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 GEMIN6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 GEMIN6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA GEMIN6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 GEMIN6 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000136174 GEMIN6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000045DBD GEMIN6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000508C13 GEMIN6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000005A8ED GEMIN6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 GEMIN6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000015188E GEMIN6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005D986D GEMIN6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A608 GEMIN6 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000032835F GEMIN6 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000753AD GEMIN6 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000048D44E GEMIN6 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001F373E GEMIN6 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SNRPD3 GEMIN6 25361965 interaction type N/A PTMCode2
GEMIN6 SNRPD3 25361965 interaction type N/A PTMCode2
GEMIN6 GEMIN4 25361965 interaction type N/A PTMCode2
GEMIN4 GEMIN6 25361965 interaction type N/A PTMCode2
GEMIN6 SNRPD2 25361965 interaction type N/A PTMCode2
SNRPD2 GEMIN6 25361965 interaction type N/A PTMCode2
GEMIN6 SMN1 25361965 interaction type N/A PTMCode2
SMN1 GEMIN6 25361965 interaction type N/A PTMCode2
GEMIN6 STRAP 25361965 interaction type N/A PTMCode2
STRAP GEMIN6 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNRPB GEMIN6 11748230 14525934 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD
CDC5L GEMIN6 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GEMIN6 GEMIN7 12065586 14525934 15939020 16189514 24234451 25348397 25416956 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,cosedimentation in solution,experimental interaction detection,molecular sieving,pull down,x-ray crystallography,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo,two hybrid prey pooling approach,validated two hybrid ComPPI,HPRD,IntAct
GEMIN6 SNRPD2 11748230 14525934 15939020 24234451 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
GEMIN6 SNRPD3 11748230 14525934 15939020 24234451 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
GEMIN6 SNRPG 14525934 15939020 24234451 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
GEMIN6 SNRPF 14525934 15939020 24234451 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
GEMIN6 STRAP 14525934 15848170 24234451 25348397 26496610 association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
GEMIN6 SNRPE 11748230 14525934 15939020 24234451 25348397 N/A experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct
GEMIN6 SMN1 19928837 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GEMIN6 GEMIN2 25348397 N/A physical interaction ComPPI
GEMIN6 DDX20 25348397 N/A physical interaction ComPPI
GEMIN6 GEMIN4 25348397 N/A physical interaction ComPPI
GEMIN6 SLX1A 19596235 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GEMIN6 ELAVL1 25348397 N/A physical interaction ComPPI
GEMIN6 GEMIN5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GEMIN6 MMS19 25348397 N/A physical interaction ComPPI
GEMIN6 EGFR 25348397 N/A physical interaction ComPPI
GEMIN6 TOX4 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GEMIN6 RAB17 25348397 N/A physical interaction ComPPI
GEMIN6 P2RY12 25348397 N/A physical interaction ComPPI
GEMIN6 F2RL1 25348397 N/A physical interaction ComPPI
GEMIN6 JAK3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GEMIN6 GPSM2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GEMIN6 GEMIN8 25348397 N/A physical interaction ComPPI
GEMIN6 SNRNP70 25348397 N/A physical interaction ComPPI
GEMIN6 NCKIPSD 25348397 N/A physical interaction ComPPI
GEMIN6 SNRPGP15 25348397 N/A physical interaction ComPPI
GEMIN6 SIGLECL1 25348397 N/A physical interaction ComPPI
GEMIN6 AVP 25348397 N/A physical interaction ComPPI
GEMIN6 NUFIP1 25348397 N/A physical interaction ComPPI
GEMIN6 SNRPD1 15939020 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
GEMIN6 RASL11B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GEMIN6 DDIT4L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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