Gene Information gene info

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GENE：GNG5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GNG5
FullNmae G protein subunit gamma 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4408
EnsembleID ENSG00000174021
Uniprot P63218

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GNG5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GNG5 GO:0003924,GO:0005515,GO:0005834,GO:0005834,GO:0005886,GO:0007165,GO:0007186,GO:0007186,GO:0016020,GO:0030165,GO:0031681,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GNG5 hsa:2787 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
GNG5 hsa:2787 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
GNG5 hsa:2787 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
GNG5 hsa:2787 path:hsa04371 Apelin signaling pathway - Homo sapiens (human)
GNG5 hsa:2787 path:hsa04713 Circadian entrainment - Homo sapiens (human)
GNG5 hsa:2787 path:hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human)
GNG5 hsa:2787 path:hsa04724 Glutamatergic synapse - Homo sapiens (human)
GNG5 hsa:2787 path:hsa04725 Cholinergic synapse - Homo sapiens (human)
GNG5 hsa:2787 path:hsa04726 Serotonergic synapse - Homo sapiens (human)
GNG5 hsa:2787 path:hsa04727 GABAergic synapse - Homo sapiens (human)
GNG5 hsa:2787 path:hsa04728 Dopaminergic synapse - Homo sapiens (human)
GNG5 hsa:2787 path:hsa04926 Relaxin signaling pathway - Homo sapiens (human)
GNG5 hsa:2787 path:hsa05032 Morphine addiction - Homo sapiens (human)
GNG5 hsa:2787 path:hsa05034 Alcoholism - Homo sapiens (human)
GNG5 hsa:2787 path:hsa05163 Human cytomegalovirus infection - Homo sapiens (human)
GNG5 hsa:2787 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)
GNG5 hsa:2787 path:hsa05170 Human immunodeficiency virus 1 infection - Homo sapiens (human)
GNG5 hsa:2787 path:hsa05200 Pathways in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 GNG5 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR GNG5 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 GNG5 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA GNG5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GNG5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GNG5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GNG5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 GNG5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 GNG5 19088304 20371350 25416803 27292025 mrna cleavage,inhibition array technology,clip TarBase
URS0000065D58 GNG5 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00001A405B GNG5 23622248 25416803 27292025 mrna cleavage,inhibition clip,clash TarBase
URS000000B1C9 GNG5 20371350 23622248 25416803 27292025 mrna cleavage,inhibition clip,clash TarBase
URS00005C1F22 GNG5 20371350 21572407 23592263 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000202460 GNG5 20371350 21572407 23592263 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000345DEB GNG5 20371350 21572407 23592263 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075BEA7 GNG5 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000020CEC2 GNG5 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000A07C1 GNG5 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000031E12 GNG5 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000324096 GNG5 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000029979D GNG5 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000237CBD GNG5 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000032EF64 GNG5 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000034979B GNG5 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000006B702 GNG5 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GNAI3 GNG5 25348397 N/A physical interaction ComPPI
GOLGA2 GNG5 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GNG5 KRT31 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GNG5 KRT40 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GNG5 MDFI 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GNG5 GNB5 14525934 25348397 8636150 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
GNG5 GNB1 14525934 24234451 25348397 25416956 8636150 physical association two hybrid,physical interaction,mammalian protein protein interaction trap,two hybrid ComPPI,HPRD,IntAct
GNG5 GNB2 14525934 25348397 8636150 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
GNG5 GNB3 14525934 25348397 8636150 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
GNG5 GNB4 14525934 25348397 8636150 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
GNG5 TRAF1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GNG5 AMOTL2 25348397 N/A physical interaction ComPPI
GNG5 EPS15L1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GNG5 ABCE1 25348397 N/A physical interaction ComPPI
GNG5 SLC25A41 25348397 N/A physical interaction ComPPI
GNG5 FSD1 25348397 N/A physical interaction ComPPI
GNG5 FYTTD1 25348397 N/A physical interaction ComPPI
GNG5 NFKBIA 25348397 N/A physical interaction ComPPI
GNG5 PPP1R3C 25348397 N/A physical interaction ComPPI
GNG5 GNAI1 25348397 N/A physical interaction ComPPI
GNG5 GNAI2 25348397 N/A physical interaction ComPPI
GNG5 GNAS 25348397 N/A physical interaction ComPPI
GNG5 GNAS 25348397 N/A physical interaction ComPPI
GNG5 GNAS 25348397 N/A physical interaction ComPPI
GNG5 COQ9 25348397 N/A physical interaction ComPPI
GNG5 S1PR1 25348397 N/A physical interaction ComPPI
GNG5 SLC6A5 25348397 N/A physical interaction ComPPI
GNG5 C1QL4 25348397 N/A physical interaction ComPPI
GNG5 IER3IP1 25348397 N/A physical interaction ComPPI
GNG5 SPRED2 25348397 N/A physical interaction ComPPI
GNG5 DUSP22 25348397 N/A physical interaction ComPPI
GNG5 PMS1 25348397 N/A physical interaction ComPPI
GNG5 COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct

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