Gene Information gene info

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GENE：ACER2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ACER2
FullNmae alkaline ceramidase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23675
EnsembleID ENSG00000177076
Uniprot Q5QJU3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ACER2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ACER2 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ACER2 autophagy 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ACER2 GO:0000139,GO:0000139,GO:0001953,GO:0005794,GO:0006919,GO:0006974,GO:0008284,GO:0010506,GO:0017040,GO:0017040,GO:0030148,GO:0030330,GO:0032526,GO:0033629,GO:0042981,GO:0046512,GO:0046512,GO:0046512,GO:0046514,GO:0046514,GO:0046872,GO:0060049,GO:0071466,GO:0071633,GO:0071633,GO:0071633,GO:0102121

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ACER2 hsa:340485 path:hsa00600 Sphingolipid metabolism - Homo sapiens (human)
ACER2 hsa:340485 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ACER2 hsa:340485 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LYL1 ACER2 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ACER2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ACER2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ACER2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ACER2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ACER2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ACER2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ACER2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ACER2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000031E12 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000A07C1 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000000B1C9 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000029979D ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000237CBD ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000052E1A6 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000076E54 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000032EF64 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000C36BD ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001FA076 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 ACER2 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A ACER2 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000045E0EC ACER2 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000334286 ACER2 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 ACER2 22012620 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000247AC6 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC379 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS000016FF9C ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001D4A78 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F ACER2 23824327 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS00000821E0 ACER2 24398324 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD ACER2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF ACER2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000029EBD ACER2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000F31F4 ACER2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000153377 ACER2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000136174 ACER2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000F7766 ACER2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Visualization










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