Gene Information gene info

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GENE：AKAP5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol AKAP5
FullNmae A-kinase anchoring protein 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:375
EnsembleID ENSG00000179841
Uniprot P24588

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
AKAP5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
AKAP5 GO:0005515,GO:0005516,GO:0005829,GO:0005829,GO:0005886,GO:0007165,GO:0007193,GO:0007194,GO:0007268,GO:0008179,GO:0008179,GO:0008287,GO:0009898,GO:0010738,GO:0014069,GO:0017124,GO:0030346,GO:0031698,GO:0032590,GO:0034237,GO:0034237,GO:0034237,GO:0035254,GO:0035254,GO:0043197,GO:0045121,GO:0045762,GO:0050811,GO:0051018,GO:0060076,GO:0060090,GO:0070886,GO:0097110,GO:0098837,GO:1900273,GO:1903078,GO:1905665,GO:1905751

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AKAP5 IQGAP1 12938160 23180781 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 AKAP5 10753752 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AKAP5 ADRB2 20005715 interaction type N/A PSP
AKAP5 RET 20005715 interaction type N/A PSP
AKAP5 PRKCA 20005715 interaction type N/A PSP
AKAP5 GABRB3 20005715 interaction type N/A PSP
AKAP5 PRKCA 11557526 18988627 20005715 20005715 N/A N/A SignaLink
AKAP5 RET 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ESR1 AKAP5 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 AKAP5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 AKAP5 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 AKAP5 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 AKAP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA AKAP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF AKAP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 AKAP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 AKAP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 AKAP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS AKAP5 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 AKAP5 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00001C0099 AKAP5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 AKAP5 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 AKAP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000027464B AKAP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001DC1D3 AKAP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E AKAP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000156390 AKAP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 AKAP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075ABF4 AKAP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 AKAP5 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC AKAP5 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000008A99 AKAP5 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005CC20C AKAP5 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001481F9 AKAP5 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075BDAA AKAP5 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000EC1BE AKAP5 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ADRB2 AKAP5 25361965 interaction type N/A PTMCode2
AKAP5 ADRB2 25361965 interaction type N/A PTMCode2
DLG4 AKAP5 25361965 interaction type N/A PTMCode2
AKAP5 DLG4 25361965 interaction type N/A PTMCode2
IQGAP1 AKAP5 25361965 interaction type N/A PTMCode2
AKAP5 IQGAP1 25361965 interaction type N/A PTMCode2
AKAP5 PPP3CA 25361965 interaction type N/A PTMCode2
PPP3CA AKAP5 25361965 interaction type N/A PTMCode2
PRKCA AKAP5 25361965 interaction type N/A PTMCode2
AKAP5 PRKCA 25361965 interaction type N/A PTMCode2
KCNJ2 AKAP5 25361965 interaction type N/A PTMCode2
AKAP5 KCNJ2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HSPA8 AKAP5 25348397 N/A physical interaction ComPPI
HSPA2 AKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2B AKAP5 11557526 14525934 25348397 26186194 27898060 8509414 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
CALM1 AKAP5 25348397 N/A physical interaction ComPPI
PRKACB AKAP5 23455922 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
TRPV4 AKAP5 25348397 N/A physical interaction ComPPI
PRKCA AKAP5 11557526 14525934 25348397 N/A coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD
PRKACA AKAP5 23455922 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
PRKAR1A AKAP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CLK1 AKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKAR2A AKAP5 11557526 12672969 14525934 16642035 1860836 22343722 24234451 25348397 26496610 27898060 association,physical association anti tag coimmunoprecipitation,biophysical,experimental interaction detection,filter binding,fluorescent resonance energy transfer,molecular sieving,physical interaction ComPPI,HPRD,IntAct,OmniPath
IQGAP1 AKAP5 12938160 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
TRPV1 AKAP5 25348397 N/A physical interaction ComPPI
PDE4D AKAP5 25348397 N/A anti bait coimmunoprecipitation ComPPI
RXFP1 AKAP5 20664520 24234451 25348397 27898060 physical association pull down ComPPI,IntAct,OmniPath
SUV39H1 AKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TNPO1 AKAP5 25348397 N/A physical interaction ComPPI
KCNJ2 AKAP5 11287423 14525934 24234451 25348397 27898060 physical association experimental interaction detection,pull down ComPPI,HPRD,IntAct,OmniPath
H3C1 AKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRPF4B AKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DERL1 AKAP5 25348397 N/A physical interaction ComPPI
PPP3R1 AKAP5 22343722 24234451 25348397 physical association light scattering,molecular sieving,x-ray crystallography ComPPI,IntAct
PPP3CA AKAP5 14525934 25348397 7528941 9765270 N/A experimental interaction detection,fluorescent resonance energy transfer,physical interaction ComPPI,HPRD
GABRB3 AKAP5 12595241 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
ROPN1 AKAP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CTDSPL AKAP5 25348397 N/A physical interaction ComPPI
TRPV2 AKAP5 25348397 N/A physical interaction ComPPI
RBMXL1 AKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IPO4 AKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LUC7L3 AKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SLC25A12 AKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MRPL43 AKAP5 25348397 N/A physical interaction ComPPI
NCL AKAP5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AKAP5 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
AKAP5 OTUD6B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AKAP5 SGMS2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AKAP5 RSBN1L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AKAP5 TRPM8 25348397 N/A physical interaction ComPPI
AKAP5 TRPA1 25348397 N/A physical interaction ComPPI
AKAP5 PRKACG 25348397 N/A physical interaction ComPPI
AKAP5 ADRB2 10753752 14525934 N/A experimental interaction detection HPRD
AKAP5 DLG1 10939335 14525934 N/A experimental interaction detection HPRD
AKAP5 CALM2 14525934 9202019 N/A experimental interaction detection HPRD
AKAP5 DLG4 10939335 14525934 N/A experimental interaction detection HPRD
GABRB1 AKAP5 12595241 14525934 N/A experimental interaction detection HPRD
RET AKAP5 11886862 14525934 N/A experimental interaction detection HPRD
AKAP5 PPP1CA 21561082 27898060 N/A N/A OmniPath
AKAP5 TRPV4 24778429 25005230 27898060 stimulant N/A OmniPath
AKAP5 TRPV1 18381233 18463244 18701070 22789851 23264624 23616546 23699529 27898060 stimulant N/A OmniPath

Visualization










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