Gene Information gene info

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GENE：CAV3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CAV3
FullNmae caveolin 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1529
EnsembleID ENSG00000182533
Uniprot P56539

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CAV3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CAV3 GO:0000139,GO:0000165,GO:0001666,GO:0001778,GO:0002027,GO:0002931,GO:0003300,GO:0005246,GO:0005515,GO:0005783,GO:0005886,GO:0005886,GO:0005901,GO:0005901,GO:0005925,GO:0006469,GO:0006641,GO:0006816,GO:0006897,GO:0007009,GO:0007015,GO:0007204,GO:0007517,GO:0007520,GO:0008016,GO:0008104,GO:0008284,GO:0009986,GO:0010614,GO:0010831,GO:0014704,GO:0014819,GO:0016010,GO:0017015,GO:0017080,GO:0017080,GO:0019870,GO:0030018,GO:0030154,GO:0030154,GO:0030315,GO:0031116,GO:0031122,GO:0031579,GO:0031594,GO:0031982,GO:0033292,GO:0035995,GO:0038009,GO:0042383,GO:0042391,GO:0042593,GO:0042632,GO:0043014,GO:0043231,GO:0043407,GO:0043409,GO:0044325,GO:0044325,GO:0044877,GO:0045121,GO:0045792,GO:0050998,GO:0051001,GO:0051394,GO:0051480,GO:0051647,GO:0051649,GO:0051896,GO:0051926,GO:0055013,GO:0055117,GO:0060090,GO:0060090,GO:0060299,GO:0060307,GO:0060347,GO:0060373,GO:0060762,GO:0061052,GO:0070836,GO:0070836,GO:0071253,GO:0071253,GO:0071417,GO:0072659,GO:0086005,GO:0090279,GO:0098909,GO:1900744,GO:1900825,GO:1900825,GO:1900826,GO:1901017,GO:1901019,GO:1901380,GO:2000009,GO:2000060,GO:2000649,GO:2001288

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CAV3 hsa:859 path:hsa04144 Endocytosis - Homo sapiens (human)
CAV3 hsa:859 path:hsa04510 Focal adhesion - Homo sapiens (human)
CAV3 hsa:859 path:hsa05020 Prion disease - Homo sapiens (human)
CAV3 hsa:859 path:hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human)
CAV3 hsa:859 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)
CAV3 hsa:859 path:hsa05410 Hypertrophic cardiomyopathy - Homo sapiens (human)
CAV3 hsa:859 path:hsa05412 Arrhythmogenic right ventricular cardiomyopathy - Homo sapiens (human)
CAV3 hsa:859 path:hsa05414 Dilated cardiomyopathy - Homo sapiens (human)
CAV3 hsa:859 path:hsa05416 Viral myocarditis - Homo sapiens (human)
CAV3 hsa:859 path:hsa05418 Fluid shear stress and atherosclerosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CAV3 INSR 20005715 interaction type N/A PSP
CAV3 PDGFRB 20005715 interaction type N/A PSP,SignaLink
CAV3 PDGFRA 20005715 interaction type N/A PSP,SignaLink
CAV3 INSR 20005715 20005715 N/A N/A SignaLink

Source Target Pmid Interactiontype Methods Database
AR CAV3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 CAV3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF CAV3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CAV3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CAV3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CAV3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CAV3 JPH2 25361965 interaction type N/A PTMCode2
JPH2 CAV3 25361965 interaction type N/A PTMCode2
CAV3 FLOT2 25361965 interaction type N/A PTMCode2
FLOT2 CAV3 25361965 interaction type N/A PTMCode2
PDGFRA CAV3 25361965 interaction type N/A PTMCode2
CAV3 PDGFRA 25361965 interaction type N/A PTMCode2
INSR CAV3 25361965 interaction type N/A PTMCode2
CAV3 INSR 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
OIP5 CAV3 25348397 N/A physical interaction ComPPI
MIS18A CAV3 25348397 N/A physical interaction ComPPI
PCBP1 CAV3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
YIPF3 CAV3 25348397 N/A physical interaction ComPPI
CAVIN3 CAV3 19262564 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
SCN5A CAV3 25348397 N/A physical interaction ComPPI
MCM10 CAV3 25348397 N/A physical interaction ComPPI
PDGFRB CAV3 25348397 N/A physical interaction ComPPI
TOM1L1 CAV3 25348397 N/A physical interaction ComPPI
PFKM CAV3 14525934 25348397 27898060 9252390 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
UBB CAV3 25348397 N/A physical interaction ComPPI
PDGFRA CAV3 25348397 N/A physical interaction ComPPI
CAV1 CAV3 25348397 N/A physical interaction ComPPI
PTGES3 CAV3 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NEDD4L CAV3 25348397 N/A physical interaction ComPPI
CAV3 SLC8A1 11821059 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
CAV3 DYSF 11532985 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
CAV3 JPH2 14525934 15541368 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
CAV3 INSR 14525934 25348397 9756945 N/A experimental interaction detection,in vitro ComPPI,HPRD
CAV3 DAG1 10988290 25348397 27898060 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
CAV3 SLC22A11 14525934 18985008 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
CAV3 SVIL 12711699 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
CAV3 EGFR 14525934 25348397 9374534 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CAV3 GNAS 14525934 25348397 7797570 N/A experimental interaction detection,in vitro ComPPI,HPRD
CAV3 NOS1 14525934 25348397 27898060 9353265 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
CAV3 ADRB2 24234451 25348397 28298427 physical association ubiquitin reconstruction,physical interaction ComPPI,IntAct
CAV3 KCNH2 25348397 N/A physical interaction ComPPI
CAV3 KCNMA1 25348397 N/A physical interaction ComPPI
CAV3 SENP1 25348397 N/A physical interaction ComPPI
CAV3 ANKRD13C 25348397 N/A physical interaction ComPPI
CAV3 ENDOD1 25348397 N/A physical interaction ComPPI
CAV3 SARM1 25348397 N/A physical interaction ComPPI
CAV3 CEP95 25348397 N/A physical interaction ComPPI
CAV3 CENPT 25348397 N/A physical interaction ComPPI
CAV3 MIS18BP1 25348397 N/A physical interaction ComPPI
CAV3 GTSE1 25348397 N/A physical interaction ComPPI
CAV3 REEP1 25348397 N/A physical interaction ComPPI
CAV3 AP1S2 25348397 N/A physical interaction ComPPI
CAV3 REEP4 25348397 N/A physical interaction ComPPI
CAV3 TBC1D2B 25348397 N/A physical interaction ComPPI
CAV3 SBDS 25348397 N/A physical interaction ComPPI
CAV3 NFRKB 25348397 N/A physical interaction ComPPI
CAV3 RAI14 25348397 N/A physical interaction ComPPI
CAV3 MAP7D3 25348397 N/A physical interaction ComPPI
CAV3 SNX3 25348397 N/A physical interaction ComPPI
CAV3 SUN2 25348397 N/A physical interaction ComPPI
CAV3 TULP3 25348397 N/A physical interaction ComPPI
CAV3 REEP2 25348397 N/A physical interaction ComPPI
CAV3 CFAP410 25348397 N/A physical interaction ComPPI
CAV3 CAVIN1 25348397 N/A physical interaction ComPPI
CAV3 SHTN1 25348397 N/A physical interaction ComPPI
CAV3 TM2D3 25348397 N/A physical interaction ComPPI
CAV3 MARK2 25348397 N/A physical interaction ComPPI
CAV3 RBFA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CAV3 GOLM1 24234451 25348397 27569582 association anti tag coimmunoprecipitation ComPPI,IntAct
KIF1B CAV3 25348397 N/A physical interaction ComPPI
SRC CAV3 14600260 27898060 8663016 N/A N/A OmniPath
TRPC1 CAV3 18544631 27898060 N/A N/A OmniPath
CAV3 GNAS 27898060 7797570 N/A N/A OmniPath

Visualization










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