GENE：DNAJB12
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | DNAJB12 |
| FullNmae | DnaJ heat shock protein family (Hsp40) member B12 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:14891 |
| EnsembleID | ENSG00000148719 |
| Uniprot | Q9NXW2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| DNAJB12 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| DNAJB12 | GO:0005783,GO:0005789,GO:0005789,GO:0016020,GO:0030544,GO:0030544,GO:0031965,GO:0036503,GO:0051085,GO:0051085,GO:0065003,GO:0071218,GO:0071218 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| DNAJB12 | hsa:54788 | path:hsa04141 | Protein processing in endoplasmic reticulum - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | DNAJB12 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | DNAJB12 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | DNAJB12 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | DNAJB12 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | DNAJB12 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HSPA8 | DNAJB12 | 25348397 | N/A | physical interaction | ComPPI |
| SGTA | DNAJB12 | 24234451 25036637 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PTPRO | DNAJB12 | 25348397 | N/A | physical interaction | ComPPI |
| DSTN | DNAJB12 | 25348397 | N/A | physical interaction | ComPPI |
| MYC | DNAJB12 | 21150319 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| TNFRSF1A | DNAJB12 | 14743216 24234451 25348397 | physical association | tandem affinity purification | ComPPI,IntAct |
| HNRNPL | DNAJB12 | 25348397 | N/A | physical interaction | ComPPI |
| CFTR | DNAJB12 | 25348397 | N/A | physical interaction | ComPPI |
| MAPK6 | DNAJB12 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| EGFR | DNAJB12 | 25348397 | N/A | physical interaction | ComPPI |
| HSPA9 | DNAJB12 | 25348397 | N/A | physical interaction | ComPPI |
| BAG4 | DNAJB12 | 24234451 25036637 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MME | DNAJB12 | 17342744 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| EYA2 | DNAJB12 | 25348397 | N/A | physical interaction | ComPPI |
| RIPK4 | DNAJB12 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| CRBN | DNAJB12 | 25348397 | N/A | physical interaction | ComPPI |
| KDM5B | DNAJB12 | 24234451 24937458 | association | chromatin immunoprecipitation assay | IntAct |