GENE:FNBP1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | FNBP1 |
| FullNmae | formin binding protein 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:17069 |
| EnsembleID | ENSG00000187239 |
| Uniprot | Q96RU3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| FNBP1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| FNBP1 | GO:0005515,GO:0005764,GO:0005829,GO:0005856,GO:0005886,GO:0005905,GO:0005938,GO:0006897,GO:0007165,GO:0008289,GO:0031410,GO:0042802,GO:0043231 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| FNBP1 | hsa:23048 | path:hsa05131 | Shigellosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | FNBP1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | FNBP1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | FNBP1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | FNBP1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | FNBP1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | FNBP1 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | FNBP1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| PRDM14 | FNBP1 | 20953172 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | FNBP1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000B59A2 | FNBP1 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000009262D | FNBP1 | 18591254 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00003D5391 | FNBP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000600E6 | FNBP1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000C85B2 | FNBP1 | 23622248 23824327 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS00001CC4BD | FNBP1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000535FDD | FNBP1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032BDF4 | FNBP1 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000345DEB | FNBP1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000036B845 | FNBP1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005D4F5 | FNBP1 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002CAE0C | FNBP1 | 23313552 23824327 24906430 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | FNBP1 | 23824327 24906430 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BD6DC | FNBP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000009EA8F | FNBP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | FNBP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004E02F2 | FNBP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000ECE9C | FNBP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000004BACE | FNBP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000001A7A | FNBP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | FNBP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | FNBP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021202F | FNBP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002D2333 | FNBP1 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005D986D | FNBP1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | FNBP1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000170CF4 | FNBP1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | FNBP1 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TNKS | FNBP1 | 25361965 | interaction type | N/A | PTMCode2 |
| FNBP1 | TNKS | 25361965 | interaction type | N/A | PTMCode2 |
| FASLG | FNBP1 | 25361965 | interaction type | N/A | PTMCode2 |
| FNBP1 | FASLG | 25361965 | interaction type | N/A | PTMCode2 |
| DNM1 | FNBP1 | 25361965 | interaction type | N/A | PTMCode2 |
| FNBP1 | DNM1 | 25361965 | interaction type | N/A | PTMCode2 |
| SNX2 | FNBP1 | 25361965 | interaction type | N/A | PTMCode2 |
| FNBP1 | SNX2 | 25361965 | interaction type | N/A | PTMCode2 |
| DNM2 | FNBP1 | 25361965 | interaction type | N/A | PTMCode2 |
| FNBP1 | DNM2 | 25361965 | interaction type | N/A | PTMCode2 |
| WAS | FNBP1 | 25361965 | interaction type | N/A | PTMCode2 |
| FNBP1 | WAS | 25361965 | interaction type | N/A | PTMCode2 |
| CDC42 | FNBP1 | 25361965 | interaction type | N/A | PTMCode2 |
| FNBP1 | CDC42 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| WASL | FNBP1 | 14525934 14732713 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| PDE6G | FNBP1 | 14502124 14525934 25348397 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD |
| CDC42 | FNBP1 | 12421766 14525934 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| WAS | FNBP1 | 25348397 | N/A | physical interaction | ComPPI |
| TUBB | FNBP1 | 25348397 | N/A | physical interaction | ComPPI |
| GABARAPL2 | FNBP1 | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| CBL | FNBP1 | 14525934 18273061 25348397 | N/A | experimental interaction detection,in vitro,in vivo | ComPPI,HPRD |
| DAAM1 | FNBP1 | 16630611 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| SNX2 | FNBP1 | 11438682 14525934 14596906 24234451 25348397 27898060 | colocalization,physical association | anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,fluorescence microscopy,in vivo,two hybrid | ComPPI,HPRD,IntAct,OmniPath |
| DNM1 | FNBP1 | 14525934 15252009 24234451 25348397 | colocalization,physical association | anti tag coimmunoprecipitation,experimental interaction detection,fluorescence technology,pull down,physical interaction,in vitro,in vivo | ComPPI,HPRD,IntAct |
| HSPA1A | FNBP1 | 25348397 | N/A | physical interaction | ComPPI |
| HSPA1B | FNBP1 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPL | FNBP1 | 25348397 | N/A | physical interaction | ComPPI |
| PPP2CA | FNBP1 | 25348397 | N/A | physical interaction | ComPPI |
| TRIP10 | FNBP1 | 18329367 24234451 25348397 27898060 | colocalization | fluorescence microscopy | ComPPI,IntAct,OmniPath |
| ITSN1 | FNBP1 | 25348397 | N/A | physical interaction | ComPPI |
| EGF | FNBP1 | 25348397 | N/A | physical interaction | ComPPI |
| FASLG | FNBP1 | 12023017 14525934 16318909 24234451 25348397 | physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo | ComPPI,HPRD,IntAct |
| SF3A1 | FNBP1 | 25348397 | N/A | physical interaction | ComPPI |
| FNBP1 | RND2 | 12244061 14525934 14732713 25348397 27898060 | N/A | two hybrid,experimental interaction detection,in vitro,two hybrid | ComPPI,HPRD,OmniPath |
| FNBP1 | TNKS | 14525934 14596906 24234451 25348397 | colocalization,physical association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,fluorescence microscopy,in vivo,two hybrid | ComPPI,HPRD,IntAct |
| FNBP1 | AKAP9 | 25348397 | N/A | physical interaction | ComPPI |
| FNBP1 | TF | 25348397 | N/A | physical interaction | ComPPI |
| FNBP1 | GABARAP | 20562859 24234451 25348397 | physical association | anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
| FNBP1 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| FNBP1 | DNM2 | 15252009 24234451 25348397 | colocalization,physical association | fluorescence technology,pull down,physical interaction | ComPPI,IntAct |
| FNBP1 | SHMT2 | 25348397 | N/A | physical interaction | ComPPI |
| FNBP1 | NXF1 | 25348397 | N/A | physical interaction | ComPPI |
| FNBP1 | FCHO1 | 25348397 | N/A | physical interaction | ComPPI |
| FNBP1 | MYO1E | 25348397 | N/A | physical interaction | ComPPI |
| FNBP1 | TMEM17 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
| FNBP1 | RBPJ | 24234451 25348397 25609649 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| FNBP1 | TRIM25 | 25348397 | N/A | physical interaction | ComPPI |
| FNBP1 | ZUP1 | 25348397 | N/A | physical interaction | ComPPI |
| FNBP1 | DNM3 | 15252009 24234451 25348397 | colocalization,physical association | fluorescence technology,pull down | ComPPI,IntAct |
| FNBP1 | GABARAPL1 | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| FNBP1 | MAP1LC3C | 20562859 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| FNBP1 | TNKS2 | 22153077 24234451 25348397 | N/A | fluorescence polarization spectroscopy | ComPPI,IntAct |
| ARHGAP17 | FNBP1 | 11431473 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro | ComPPI,HPRD |
| FNBP1 | FNBP1 | 12023017 14525934 15252009 17512409 24234451 | physical association | anti tag coimmunoprecipitation,cosedimentation in solution,experimental interaction detection,x-ray crystallography | HPRD,IntAct |
| FNBP1 | AGTR1 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |
| FNBP1 | FASLG | 12023017 16318909 24291222 27898060 | N/A | N/A | OmniPath |
