GENE：GABRA2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | GABRA2 |
| FullNmae | gamma-aminobutyric acid type A receptor subunit alpha2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:4076 |
| EnsembleID | ENSG00000151834 |
| Uniprot | P47869 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| GABRA2 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| GABRA2 | GO:0001505,GO:0004890,GO:0005237,GO:0005254,GO:0005515,GO:0005886,GO:0006836,GO:0007165,GO:0007214,GO:0007214,GO:0008503,GO:0022851,GO:0022851,GO:0030424,GO:0030672,GO:0032590,GO:0034707,GO:0043005,GO:0043025,GO:0045202,GO:0050877,GO:0051932,GO:0060077,GO:0060078,GO:0098794,GO:0098982,GO:0099505,GO:0099507,GO:0099507,GO:0099507,GO:0099634,GO:1902476,GO:1902476,GO:1902711,GO:1902711,GO:1904315,GO:1904315,GO:1904862 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| GABRA2 | hsa:2555 | path:hsa04080 | Neuroactive ligand-receptor interaction - Homo sapiens (human) |
| GABRA2 | hsa:2555 | path:hsa04723 | Retrograde endocannabinoid signaling - Homo sapiens (human) |
| GABRA2 | hsa:2555 | path:hsa04727 | GABAergic synapse - Homo sapiens (human) |
| GABRA2 | hsa:2555 | path:hsa04742 | Taste transduction - Homo sapiens (human) |
| GABRA2 | hsa:2555 | path:hsa05032 | Morphine addiction - Homo sapiens (human) |
| GABRA2 | hsa:2555 | path:hsa05033 | Nicotine addiction - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| YBX1 | GABRA2 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| CEBPA | GABRA2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | GABRA2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | GABRA2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00001DE669 | GABRA2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CF5F | GABRA2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000065D58 | GABRA2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000153377 | GABRA2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E1509 | GABRA2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000016914 | GABRA2 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |