Gene Information gene info

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GENE：ISL2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ISL2
FullNmae ISL LIM homeobox 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18524
EnsembleID ENSG00000159556
Uniprot Q96A47

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ISL2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ISL2 GO:0000785,GO:0000981,GO:0000981,GO:0000987,GO:0003677,GO:0005515,GO:0005634,GO:0005634,GO:0007409,GO:0021520,GO:0021524,GO:0031290,GO:0045665,GO:0045944,GO:0046872,GO:0048665,GO:0048666,GO:0048935,GO:1990837

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ISL2 EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 ISL2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 ISL2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ISL2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA ISL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ISL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ISL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ISL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ISL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ISL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000015A0D9 ISL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D ISL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 ISL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F ISL2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000004DB7E ISL2 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ISL2 LDB1 25361965 interaction type N/A PTMCode2
LDB1 ISL2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LHX4 ISL2 25348397 N/A physical interaction ComPPI
COPS5 ISL2 25348397 N/A physical interaction ComPPI
LMO2 ISL2 25348397 N/A physical interaction ComPPI
ISL1 ISL2 14525934 25348397 9452425 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
LHX3 ISL2 14525934 25348397 9452425 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ISL2 IDI2 25348397 N/A physical interaction ComPPI
ISL2 SSBP2 25348397 N/A physical interaction ComPPI
ISL2 SSBP4 25348397 N/A physical interaction ComPPI
ISL2 SSBP3 25348397 N/A physical interaction ComPPI
ISL2 ARIH1 25348397 N/A physical interaction ComPPI
ISL2 ISL2 14525934 9452425 N/A experimental interaction detection HPRD
LHX3 ISL2 27898060 9452425 stimulant N/A OmniPath

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