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GENE：MCOLN2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MCOLN2
FullNmae mucolipin TRP cation channel 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13357
EnsembleID ENSG00000153898
Uniprot Q8IZK6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MCOLN2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MCOLN2 GO:0002250,GO:0005262,GO:0005886,GO:0015031,GO:0016020,GO:0031902,GO:0042802,GO:0045087,GO:0051209,GO:0055038,GO:0070588,GO:0071639,GO:0071642,GO:0071651,GO:0072345,GO:1905517,GO:1990266,GO:2000343

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MCOLN2 hsa:255231 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MCOLN2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 MCOLN2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 MCOLN2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 MCOLN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MCOLN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MCOLN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MCOLN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MCOLN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MCOLN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MCOLN2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002FC5B0 MCOLN2 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00000F7766 MCOLN2 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000029EBD MCOLN2 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 MCOLN2 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 MCOLN2 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F MCOLN2 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000031B6ED MCOLN2 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003E2232 MCOLN2 20371350 21572407 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000015D23B MCOLN2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000C0D3F MCOLN2 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD MCOLN2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000008A99 MCOLN2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000122F23 MCOLN2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075B538 MCOLN2 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MCOLN2 MCOLN1 16606612 19557826 19885840 20736310 27898060 stimulant N/A OmniPath
MCOLN1 MCOLN2 16606612 19557826 19885840 20736310 27898060 stimulant N/A OmniPath

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