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GENE：NUDT12

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NUDT12
FullNmae nudix hydrolase 12
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18826
EnsembleID ENSG00000112874
Uniprot Q9BQG2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NUDT12 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NUDT12 GO:0000210,GO:0000287,GO:0005515,GO:0005634,GO:0005737,GO:0005777,GO:0005777,GO:0005782,GO:0006402,GO:0006734,GO:0006742,GO:0006742,GO:0008270,GO:0019677,GO:0019677,GO:0032922,GO:0034356,GO:0035529,GO:0035529,GO:0035529,GO:0110153,GO:0110155,GO:0110156,GO:1990174

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
NUDT12 hsa:83594 path:hsa00760 Nicotinate and nicotinamide metabolism - Homo sapiens (human)
NUDT12 hsa:83594 path:hsa01100 Metabolic pathways - Homo sapiens (human)
NUDT12 hsa:83594 path:hsa04146 Peroxisome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BLMH NUDT12 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 NUDT12 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NUDT12 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 NUDT12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NUDT12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NUDT12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NUDT12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NUDT12 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 NUDT12 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000CBE63 NUDT12 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC NUDT12 22100165 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BLMH NUDT12 24234451 25348397 25416956 25910212 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
NUDT12 PDLIM1 25348397 N/A physical interaction ComPPI
NUDT12 FKBP15 25348397 N/A physical interaction ComPPI
NUDT12 VWA8 25348397 N/A physical interaction ComPPI
NUDT12 TJP2 25348397 N/A physical interaction ComPPI
NUDT12 SIRT2 25348397 N/A physical interaction ComPPI
NUDT12 PTP4A1 25348397 N/A physical interaction ComPPI
NUDT12 KERA 25348397 N/A physical interaction ComPPI
NUDT12 ADD2 25348397 N/A physical interaction ComPPI
NUDT12 ZNF517 25348397 N/A physical interaction ComPPI
NUDT12 HSPB8 25348397 N/A physical interaction ComPPI
NUDT12 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
NCOA5 NUDT12 25348397 N/A physical interaction ComPPI
LZTR1 NUDT12 25348397 N/A physical interaction ComPPI
AHNAK NUDT12 24234451 30021884 physical association cross-linking study IntAct

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