GENE：RNF220
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RNF220 |
| FullNmae | ring finger protein 220 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:25552 |
| EnsembleID | ENSG00000187147 |
| Uniprot | Q5VTB9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RNF220 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RNF220 | GO:0003358,GO:0004842,GO:0005515,GO:0005634,GO:0005652,GO:0005737,GO:0006513,GO:0008013,GO:0016567,GO:0016567,GO:0021904,GO:0032991,GO:0046872,GO:0051091,GO:0051865,GO:0061630,GO:0090263,GO:2000677 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | RNF220 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | RNF220 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | RNF220 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | RNF220 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | RNF220 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | RNF220 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETS1 | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | RNF220 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000DDD35 | RNF220 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000065D58 | RNF220 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005CF5F | RNF220 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | RNF220 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001DE669 | RNF220 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| UBE2E2 | RNF220 | 19549727 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| UBE2E3 | RNF220 | 19549727 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| USP7 | RNF220 | 14525934 16713569 19615732 24234451 25266658 25348397 27898060 | physical association | anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct,OmniPath |
| GSK3B | RNF220 | 25348397 | N/A | physical interaction | ComPPI |
| CTNNB1 | RNF220 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2D3 | RNF220 | 25348397 | N/A | physical interaction | ComPPI |
| SIN3B | RNF220 | 20170641 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| TRIM25 | RNF220 | 25348397 | N/A | physical interaction | ComPPI |
| GOPC | RNF220 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2E1 | RNF220 | 19549727 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| ZC4H2 | RNF220 | 25348397 | N/A | physical interaction | ComPPI |
| RNF220 | WDR5B | 25348397 | N/A | physical interaction | ComPPI |
| RNF220 | CLEC3A | 25348397 | N/A | physical interaction | ComPPI |
| RNF220 | UBE2W | 19549727 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| PTGER4 | RNF220 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |