Gene Information gene info

GENE:TTC1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TTC1
FullNmae tetratricopeptide repeat domain 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12391
EnsembleID ENSG00000113312
Uniprot Q99614

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TTC1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TTC1 GO:0005515,GO:0005778,GO:0005829,GO:0006457,GO:0051082

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HRAS TTC1 12748287 23180781 physical association anti tag coimmunoprecipitation InnateDB
GNA15 TTC1 12748287 23180781 physical association anti tag coimmunoprecipitation,two hybrid,gst pull down InnateDB
GNAI2 TTC1 12748287 23180781 physical association anti tag coimmunoprecipitation InnateDB
TTC1 GNAQ 12748287 23180781 physical association anti tag coimmunoprecipitation InnateDB
TTC1 GNAS 12748287 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 TTC1 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TTC1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 TTC1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP53 TTC1 18922183 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 TTC1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 TTC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TTC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TTC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TTC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TTC1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000041CB9C TTC1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 TTC1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
TTC1 GNA11 25361965 interaction type N/A PTMCode2
GNA11 TTC1 25361965 interaction type N/A PTMCode2
TTC1 GNAI1 25361965 interaction type N/A PTMCode2
GNAI1 TTC1 25361965 interaction type N/A PTMCode2
TTC1 CRY2 25361965 interaction type N/A PTMCode2
CRY2 TTC1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MOS TTC1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HSPA8 TTC1 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
HSPA2 TTC1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SYT11 TTC1 25348397 N/A physical interaction ComPPI
ZNRD2 TTC1 25348397 N/A physical interaction ComPPI
BAG3 TTC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TOMM22 TTC1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
H4C1 TTC1 25348397 N/A physical interaction ComPPI
TTC1 HRAS 12748287 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TTC1 GNAQ 12748287 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TTC1 ACY1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TTC1 GNA15 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
TTC1 GNAS 12748287 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TTC1 GNAI2 12748287 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
TTC1 HSPA1A 14503850 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
TTC1 HSPA1B 25348397 N/A in vitro ComPPI
TTC1 HSPA4 25348397 N/A physical interaction ComPPI
TTC1 GNAS 25348397 N/A physical interaction ComPPI
TTC1 GNAS 25348397 N/A physical interaction ComPPI
TTC1 CRY2 25348397 N/A physical interaction ComPPI
TTC1 SREBF2 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TTC1 SH3BP4 18654987 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TTC1 SPP1 25348397 N/A physical interaction ComPPI
TTC1 SRXN1 25348397 N/A physical interaction ComPPI
TTC1 AHCYL1 25348397 N/A physical interaction ComPPI
TTC1 THOC3 25348397 N/A physical interaction ComPPI
TTC1 NUDCD2 25348397 N/A physical interaction ComPPI
TTC1 UBXN1 25348397 N/A physical interaction ComPPI
TTC1 ZFYVE19 25348397 N/A physical interaction ComPPI
TTC1 ZRANB2 25348397 N/A physical interaction ComPPI
TTC1 SULT1A1 25348397 N/A physical interaction ComPPI
TTC1 PAICS 25348397 N/A physical interaction ComPPI
TTC1 THOC2 25348397 N/A physical interaction ComPPI
TTC1 UBE2B 25348397 N/A physical interaction ComPPI
TTC1 SEC23A 25348397 N/A physical interaction ComPPI
TTC1 SEC24A 25348397 N/A physical interaction ComPPI
TTC1 UFM1 25348397 N/A physical interaction ComPPI
TTC1 TRIP6 25348397 N/A physical interaction ComPPI
TTC1 TTLL12 25348397 N/A physical interaction ComPPI
TTC1 UBE2D2 25348397 N/A physical interaction ComPPI
TTC1 UBQLN2 25348397 N/A physical interaction ComPPI
TTC1 UCHL3 25348397 N/A physical interaction ComPPI
TTC1 DSTN 25348397 N/A physical interaction ComPPI
TTC1 PSAT1 25348397 N/A physical interaction ComPPI
TTC1 PEX14 21525035 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
TTC1 SOX5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TTC1 PPP6R2 24234451 24255178 25348397 colocalization physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TTC1 AARSD1 25348397 N/A physical interaction ComPPI
TTC1 CARS1 25348397 N/A physical interaction ComPPI
TTC1 EFTUD2 25348397 N/A physical interaction ComPPI
TTC1 GFPT1 25348397 N/A physical interaction ComPPI
TTC1 HARS1 25348397 N/A physical interaction ComPPI
TTC1 RPUSD2 25348397 N/A physical interaction ComPPI
TTC1 SARS1 25348397 N/A physical interaction ComPPI
TTC1 SH3GL1 25348397 N/A physical interaction ComPPI
TTC1 SHMT1 25348397 N/A physical interaction ComPPI
TTC1 SNF8 25348397 N/A physical interaction ComPPI
TTC1 CUL4B 25348397 N/A physical interaction ComPPI
TTC1 EIF3J 25348397 N/A physical interaction ComPPI
TTC1 GARS1 25348397 N/A physical interaction ComPPI
TTC1 GTF2E1 25348397 N/A physical interaction ComPPI
TTC1 NCBP1 25348397 N/A physical interaction ComPPI
TTC1 OSBP 25348397 N/A physical interaction ComPPI
TTC1 PPM1G 25348397 N/A physical interaction ComPPI
TTC1 PPP2CB 25348397 N/A physical interaction ComPPI
TTC1 VAT1 25348397 N/A physical interaction ComPPI
TTC1 XPO5 25348397 N/A physical interaction ComPPI
TTC1 VAPB 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TTC1 HSPA4L 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TTC1 VAPA 24234451 25036637 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TTC1 RNF41 24234451 25036637 25348397 25416956 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TTC1 TUBA1A 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TTC1 BAG2 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TTC1 NDE1 25348397 N/A physical interaction ComPPI
TTC1 SRPRB 25348397 N/A physical interaction ComPPI
TTC1 SPSB2 25348397 N/A physical interaction ComPPI
TTC1 SETDB1 25348397 N/A physical interaction ComPPI
TTC1 INPP5A 25348397 N/A physical interaction ComPPI
TTC1 PDIA6 25348397 N/A physical interaction ComPPI
TTC1 EVC2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TTC1 XPO1 25348397 N/A physical interaction ComPPI
TTC1 HIF1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TTC1 HSP90AA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TTC1 HSP90AA2P 25348397 N/A physical interaction ComPPI
TTC1 CBX4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TTC1 SIKE1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TTC1 QSOX2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TTC1 LIMK2 25348397 N/A physical interaction ComPPI
TTC1 PCCA 25348397 N/A physical interaction ComPPI
TTC1 SULT1A3 25348397 N/A physical interaction ComPPI
TTC1 NLRP12 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TTC1 SIM2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TTC1 USP18 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TTC1 DNM3 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
TTC1 CYB5R1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TTC1 TOMM20 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
KCNJ10 TTC1 25348397 N/A physical interaction ComPPI
KPNA6 TTC1 25348397 N/A physical interaction ComPPI
XPO7 TTC1 25348397 N/A physical interaction ComPPI
NEK8 TTC1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
TGFBR1 TTC1 14525934 15761153 N/A experimental interaction detection HPRD
GNAI2 TTC1 12748287 27898060 N/A N/A OmniPath
TTC1 GNAI2 12748287 27898060 N/A N/A OmniPath
HRAS TTC1 12748287 27898060 N/A N/A OmniPath
TTC1 HRAS 12748287 27898060 N/A N/A OmniPath

Visualization