GENE：AGPAT5
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | AGPAT5 |
| FullNmae | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:20886 |
| EnsembleID | ENSG00000155189 |
| Uniprot | Q9NUQ2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| AGPAT5 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| AGPAT5 | GO:0002244,GO:0003841,GO:0003841,GO:0003841,GO:0005515,GO:0005635,GO:0005730,GO:0005739,GO:0005739,GO:0005741,GO:0005783,GO:0005789,GO:0005789,GO:0006639,GO:0006654,GO:0008654,GO:0012505,GO:0016024,GO:0016746,GO:0036149 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| AGPAT5 | hsa:55326 | path:hsa00561 | Glycerolipid metabolism - Homo sapiens (human) |
| AGPAT5 | hsa:55326 | path:hsa00564 | Glycerophospholipid metabolism - Homo sapiens (human) |
| AGPAT5 | hsa:55326 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| AGPAT5 | hsa:55326 | path:hsa04072 | Phospholipase D signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | AGPAT5 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | AGPAT5 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | AGPAT5 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | AGPAT5 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | AGPAT5 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HIF1A | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | AGPAT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000ED600 | AGPAT5 | 20215506 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00000B59A2 | AGPAT5 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS000041CB9C | AGPAT5 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000000B1C9 | AGPAT5 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001597DC | AGPAT5 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000006FDD4 | AGPAT5 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000015F70F | AGPAT5 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001BCAC5 | AGPAT5 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004407DC | AGPAT5 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BDA4 | AGPAT5 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003ABC4 | AGPAT5 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AF715 | AGPAT5 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029979D | AGPAT5 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000157F5 | AGPAT5 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003677B2 | AGPAT5 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000002569A | AGPAT5 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000453664 | AGPAT5 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000E7139 | AGPAT5 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075994C | AGPAT5 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021D7C8 | AGPAT5 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AGPAT5 | ELAVL1 | 25348397 | N/A | physical interaction | ComPPI |
| AGPAT5 | UBQLN1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| AGPAT5 | BSG | 25348397 | N/A | physical interaction | ComPPI |
| AGPAT5 | CD70 | 25348397 | N/A | physical interaction | ComPPI |
| AGPAT5 | E2F3 | 22157815 24234451 25348397 | association | pull down | ComPPI,IntAct |
| AGPAT5 | CREB3L1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |