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GENE：ALDH8A1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ALDH8A1
FullNmae aldehyde dehydrogenase 8 family member A1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15471
EnsembleID ENSG00000118514
Uniprot Q9H2A2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ALDH8A1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ALDH8A1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ALDH8A1 GO:0001758,GO:0001758,GO:0001758,GO:0005829,GO:0042573,GO:0042573,GO:0042574,GO:0042904,GO:0047102,GO:0070062,GO:0097053

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ALDH8A1 hsa:64577 path:hsa00380 Tryptophan metabolism - Homo sapiens (human)
ALDH8A1 hsa:64577 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ALDH8A1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 ALDH8A1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ALDH8A1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ALDH8A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ALDH8A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ALDH8A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ALDH8A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ALDH8A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ALDH8A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ALDH8A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 ALDH8A1 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
SMC4 ALDH8A1 25348397 N/A physical interaction ComPPI
CNN2 ALDH8A1 25348397 N/A physical interaction ComPPI
ALDH5A1 ALDH8A1 25348397 N/A physical interaction ComPPI
APP ALDH8A1 25348397 N/A physical interaction ComPPI
ADSL ALDH8A1 25348397 N/A physical interaction ComPPI
LRRK2 ALDH8A1 24234451 24725412 25348397 association tandem affinity purification ComPPI,IntAct
RPUSD2 ALDH8A1 25348397 N/A physical interaction ComPPI

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