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GENE：ARHGEF18

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARHGEF18
FullNmae Rho/Rac guanine nucleotide exchange factor 18
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17090
EnsembleID ENSG00000104880
Uniprot Q6ZSZ5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARHGEF18 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ARHGEF18 GO:0005085,GO:0005515,GO:0005829,GO:0005829,GO:0005856,GO:0005886,GO:0005886,GO:0007264,GO:0008360,GO:0016324,GO:0030036,GO:0030054,GO:0035023,GO:0045177,GO:0046872,GO:0051497,GO:0070062,GO:0150105

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ARHGEF18 hsa:23370 path:hsa04530 Tight junction - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ARHGEF18 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ARHGEF18 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 ARHGEF18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ARHGEF18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ARHGEF18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ARHGEF18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ARHGEF18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ARHGEF18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ARHGEF18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ARHGEF18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ARHGEF18 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000170CF4 ARHGEF18 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA ARHGEF18 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F ARHGEF18 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 ARHGEF18 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 ARHGEF18 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 ARHGEF18 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 ARHGEF18 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000547F6A ARHGEF18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 ARHGEF18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F ARHGEF18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000411672 ARHGEF18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00004E008F ARHGEF18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 ARHGEF18 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B ARHGEF18 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RHOA ARHGEF18 11085924 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
ARHGEF18 GNB1 14512443 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
ARHGEF18 TAF10 25348397 N/A physical interaction ComPPI
ARHGEF18 TERF1 25348397 N/A physical interaction ComPPI
ARHGEF18 LTBR 25348397 N/A physical interaction ComPPI
ARHGEF18 HNRNPL 25348397 N/A physical interaction ComPPI
MKI67 ARHGEF18 24234451 26949251 association anti tag coimmunoprecipitation IntAct
SEPTIN9 ARHGEF18 15558029 27898060 inhibition N/A OmniPath

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