GENE：ARL6
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ARL6 |
| FullNmae | ADP ribosylation factor like GTPase 6 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:13210 |
| EnsembleID | ENSG00000113966 |
| Uniprot | Q9H0F7 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ARL6 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ARL6 | GO:0003924,GO:0005515,GO:0005525,GO:0005525,GO:0005543,GO:0005737,GO:0005737,GO:0005879,GO:0005886,GO:0005929,GO:0005929,GO:0005930,GO:0005930,GO:0006612,GO:0006886,GO:0007368,GO:0007601,GO:0015630,GO:0016020,GO:0016055,GO:0016192,GO:0030117,GO:0032402,GO:0046872,GO:0051258,GO:0060271,GO:0060271,GO:0060271,GO:0061512,GO:0061512,GO:0070062 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | ARL6 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| HIF1A | ARL6 | 18971253 19828020 | trascriptional regulation,stimulation | chromatin immunoprecipitation array,inferred by curator | TFlink |
| YBX1 | ARL6 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ARL6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ARL6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ARL6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ARL6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| BBS2 | ARL6 | 22139371 24234451 25348397 | colocalization,association | anti tag coimmunoprecipitation,cosedimentation through density gradient | ComPPI,IntAct |
| SEC61B | ARL6 | 10508919 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| BBS4 | ARL6 | 22139371 24234451 25348397 | colocalization,association | anti tag coimmunoprecipitation,cosedimentation through density gradient | ComPPI,IntAct |
| ARL6 | ARL6IP4 | 25348397 | N/A | two hybrid,physical interaction | ComPPI |
| ARL6 | TOR1AIP2 | 24234451 25348397 27173435 | association,physical association | physical interaction,tandem affinity purification,inference by socio-affinity scoring | ComPPI,IntAct |
| ARL6 | SART1 | 24234451 25348397 27173435 | association,physical association | physical interaction,tandem affinity purification,inference by socio-affinity scoring | ComPPI,IntAct |
| ARL6 | BBS7 | 22139371 24234451 25348397 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| ARL6 | BBS9 | 22139371 24234451 25348397 | colocalization | cosedimentation through density gradient | ComPPI,IntAct |