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GENE：ARPC5L

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARPC5L
FullNmae actin related protein 2/3 complex subunit 5 like
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23366
EnsembleID ENSG00000136950
Uniprot Q9BPX5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARPC5L immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ARPC5L GO:0003674,GO:0005515,GO:0005737,GO:0005885,GO:0005925,GO:0008150,GO:0016477,GO:0030833,GO:0034314,GO:0051015,GO:0070062,GO:0098978

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ARPC5L hsa:81873 path:hsa04144 Endocytosis - Homo sapiens (human)
ARPC5L hsa:81873 path:hsa04530 Tight junction - Homo sapiens (human)
ARPC5L hsa:81873 path:hsa04666 Fc gamma R-mediated phagocytosis - Homo sapiens (human)
ARPC5L hsa:81873 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
ARPC5L hsa:81873 path:hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human)
ARPC5L hsa:81873 path:hsa05130 Pathogenic Escherichia coli infection - Homo sapiens (human)
ARPC5L hsa:81873 path:hsa05131 Shigellosis - Homo sapiens (human)
ARPC5L hsa:81873 path:hsa05132 Salmonella infection - Homo sapiens (human)
ARPC5L hsa:81873 path:hsa05135 Yersinia infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ESR1 ARPC5L 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ARPC5L 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ARPC5L 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC ARPC5L 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ARPC5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ARPC5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ARPC5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ARPC5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ARPC5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ARPC5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ARPC5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ARPC5L N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 ARPC5L 20065103 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000237AF9 ARPC5L 20065103 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00003D5391 ARPC5L 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C85B2 ARPC5L 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
ARPC3 ARPC5L 24234451 25348397 26655834 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GADD45G ARPC5L 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KEAP1 ARPC5L 25348397 N/A physical interaction ComPPI
FLNA ARPC5L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRKACA ARPC5L 25348397 N/A physical interaction ComPPI
IQGAP1 ARPC5L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CFTR ARPC5L 25348397 N/A physical interaction ComPPI
PDLIM7 ARPC5L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPO1 ARPC5L 25348397 N/A physical interaction ComPPI
ARRB2 ARPC5L 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK2 ARPC5L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTR3 ARPC5L 24234451 25348397 26655834 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC1B ARPC5L 24234451 25348397 26655834 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,molecular sieving,pull down,physical interaction,ion exchange chromatography ComPPI,IntAct
SH3GL1 ARPC5L 25348397 N/A physical interaction ComPPI
SYNPO ARPC5L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTR2 ARPC5L 24234451 25348397 26496610 26655834 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC5 ARPC5L 25348397 N/A physical interaction ComPPI
UFD1 ARPC5L 25348397 N/A physical interaction ComPPI
MYH9 ARPC5L 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC2 ARPC5L 24234451 25348397 26655834 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC4 ARPC5L 14525934 16169070 24234451 25348397 26655834 30021884 association,physical association anti tag coimmunoprecipitation,two hybrid,cross-linking study,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
ARPC5L ACTR3B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC5L MOV10 25348397 N/A physical interaction ComPPI
ARPC5L NXF1 25348397 N/A physical interaction ComPPI
ARPC5L CAPZB 25348397 N/A physical interaction ComPPI
ARPC5L CAPZA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC5L DBN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC5L LIMA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARPC5L BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
CALU ARPC5L 25348397 N/A physical interaction ComPPI

Visualization










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