Gene Information gene info

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GENE：C1QB

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol C1QB
FullNmae complement C1q B chain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1242
EnsembleID ENSG00000173369
Uniprot P02746

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
C1QB immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
C1QB GO:0005515,GO:0005576,GO:0005576,GO:0005576,GO:0005581,GO:0005602,GO:0006956,GO:0006958,GO:0006958,GO:0045087,GO:0045202,GO:0062023,GO:0062167,GO:0072562,GO:0098794,GO:0098883

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
C1QB hsa:713 path:hsa04148 Efferocytosis - Homo sapiens (human)
C1QB hsa:713 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
C1QB hsa:713 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
C1QB hsa:713 path:hsa05020 Prion disease - Homo sapiens (human)
C1QB hsa:713 path:hsa05133 Pertussis - Homo sapiens (human)
C1QB hsa:713 path:hsa05142 Chagas disease - Homo sapiens (human)
C1QB hsa:713 path:hsa05150 Staphylococcus aureus infection - Homo sapiens (human)
C1QB hsa:713 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
C1QB hsa:713 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 C1QB 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 C1QB 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF C1QB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 C1QB 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS C1QB 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 C1QB 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
C1QB C1QC 25361965 interaction type N/A PTMCode2
C1QC C1QB 25361965 interaction type N/A PTMCode2
C1QB C1QA 25361965 interaction type N/A PTMCode2
C1QA C1QB 25361965 interaction type N/A PTMCode2
PTX3 C1QB 25361965 interaction type N/A PTMCode2
C1QB PTX3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
P3H4 C1QB 25348397 N/A physical interaction ComPPI
COL4A2 C1QB 25348397 N/A physical interaction ComPPI
METAP2 C1QB 25348397 N/A physical interaction ComPPI
RELA C1QB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
C1QA C1QB 12960167 14525934 21054788 24234451 25348397 7240 association,physical association affinity chromatography technology,experimental interaction detection,x-ray crystallography,enzyme linked immunosorbent assay,in vitro,enzymatic footprinting ComPPI,HPRD,IntAct
UBQLN2 C1QB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VHL C1QB 25348397 N/A physical interaction ComPPI
EED C1QB 25348397 N/A physical interaction ComPPI
C1R C1QB 1370572 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
EDA2R C1QB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MYOC C1QB 14525934 16289162 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
DEFA1 C1QB 14525934 25348397 27898060 9444979 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
PTX3 C1QB 12645945 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
C1QB C1QC 12960167 14525934 24234451 25348397 28325905 physical association experimental interaction detection,filter binding,in vitro ComPPI,HPRD,IntAct
C1QB HRG 14525934 25348397 9184145 N/A experimental interaction detection,in vivo ComPPI,HPRD
C1QB FN1 25348397 N/A physical interaction ComPPI
C1QB IL32 25348397 N/A physical interaction ComPPI
C1QB ATP12A 25348397 N/A physical interaction ComPPI
C1QB USP30 25348397 N/A physical interaction ComPPI
C1QB GK 25348397 N/A physical interaction ComPPI
C1QB C6ORF120 25348397 N/A physical interaction ComPPI
C1QB P3H3 25348397 N/A physical interaction ComPPI
C1QB NOCT 25348397 N/A physical interaction ComPPI
C1QB DMWD 25348397 N/A physical interaction ComPPI
COLGALT2 C1QB 25348397 N/A physical interaction ComPPI
C1QB LRP1 11560994 27898060 N/A N/A OmniPath

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