Gene Information gene info

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GENE：C1QC

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol C1QC
FullNmae complement C1q C chain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1245
EnsembleID ENSG00000159189
Uniprot P02747

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
C1QC immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
C1QC GO:0005515,GO:0005576,GO:0005576,GO:0005576,GO:0005581,GO:0005602,GO:0005615,GO:0006955,GO:0006958,GO:0006958,GO:0030853,GO:0045087,GO:0045202,GO:0045650,GO:0062023,GO:0062167,GO:0072562,GO:0098794,GO:0098883

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
C1QC hsa:714 path:hsa04148 Efferocytosis - Homo sapiens (human)
C1QC hsa:714 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
C1QC hsa:714 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
C1QC hsa:714 path:hsa05020 Prion disease - Homo sapiens (human)
C1QC hsa:714 path:hsa05133 Pertussis - Homo sapiens (human)
C1QC hsa:714 path:hsa05142 Chagas disease - Homo sapiens (human)
C1QC hsa:714 path:hsa05150 Staphylococcus aureus infection - Homo sapiens (human)
C1QC hsa:714 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
C1QC hsa:714 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ELANE C1QC 19506020 23180781 physical association two hybrid InnateDB
PTX3 C1QC 12645945 23180781 physical association solid phase assay InnateDB
AGER C1QC 22386596 23180781 physical association unspecified method,surface plasmon resonance array InnateDB

Source Target Pmid Interactiontype Methods Database
PRDM14 C1QC 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF C1QC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 C1QC 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
C1QC C1QA 25361965 interaction type N/A PTMCode2
C1QA C1QC 25361965 interaction type N/A PTMCode2
C1QB C1QC 25361965 interaction type N/A PTMCode2
C1QC C1QB 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
APOA1 C1QC 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP1CA C1QC 24234451 25348397 25593058 association anti bait coimmunoprecipitation ComPPI,IntAct
C1QA C1QC 12960167 14525934 21054788 24234451 25348397 28325905 association,physical association affinity chromatography technology,experimental interaction detection,filter binding,x-ray crystallography,enzyme linked immunosorbent assay,in vitro ComPPI,HPRD,IntAct
UBQLN2 C1QC 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FKBP2 C1QC 14525934 15353007 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
PTX3 C1QC 12645945 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
C1QB C1QC 12960167 14525934 24234451 25348397 28325905 physical association experimental interaction detection,filter binding,in vitro ComPPI,HPRD,IntAct
C1QC FN1 25348397 N/A physical interaction ComPPI
C1QC ZNF534 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
C1QC C1QC 24234451 7240 N/A enzymatic footprinting IntAct

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