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GENE：C7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol C7
FullNmae complement C7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1346
EnsembleID ENSG00000112936
Uniprot P10643

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
C7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
C7 GO:0005576,GO:0005579,GO:0005579,GO:0005579,GO:0005615,GO:0005886,GO:0006956,GO:0006957,GO:0006958,GO:0031640,GO:0050778,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
C7 hsa:730 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
C7 hsa:730 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
C7 hsa:730 path:hsa05020 Prion disease - Homo sapiens (human)
C7 hsa:730 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
C7 hsa:730 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 C7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 C7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF C7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 C7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 C7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001938D9 C7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003B59DF C7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001C0099 C7 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000015A0D9 C7 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
C5 C7 25361965 interaction type N/A PTMCode2
C7 C5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PLG C7 14525934 25348397 27898060 7814888 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
CLU C7 25348397 N/A physical interaction,in vitro ComPPI
NTRK1 C7 25348397 N/A physical interaction ComPPI
C7 LPA 25348397 N/A physical interaction ComPPI
C5 C7 1387399 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD

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