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GENE：C8A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol C8A
FullNmae complement C8 alpha chain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1352
EnsembleID ENSG00000157131
Uniprot P07357

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
C8A immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
C8A GO:0001848,GO:0005515,GO:0005576,GO:0005579,GO:0005579,GO:0005579,GO:0005615,GO:0005886,GO:0006955,GO:0006956,GO:0006956,GO:0006957,GO:0006958,GO:0016020,GO:0031640,GO:0044877,GO:0050778,GO:0070062,GO:0072562

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
C8A hsa:731 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
C8A hsa:731 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
C8A hsa:731 path:hsa05020 Prion disease - Homo sapiens (human)
C8A hsa:731 path:hsa05146 Amoebiasis - Homo sapiens (human)
C8A hsa:731 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
C8A hsa:731 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HIF1A C8A 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA C8A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A C8A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 C8A 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS0000007340 C8A 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00002F74F1 C8A 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000034B6F5 C8A 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC C8A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 C8A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000029D793 C8A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 C8A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 C8A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 C8A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000170D8B C8A 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B C8A 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CD59 C8A 14525934 25348397 7544344 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
C8A C8B 10387094 25348397 27898060 N/A in vitro,in vivo ComPPI,OmniPath

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