Gene Information gene info

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GENE：C8B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol C8B
FullNmae complement C8 beta chain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1353
EnsembleID ENSG00000021852
Uniprot P07358

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
C8B immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
C8B GO:0005576,GO:0005579,GO:0005579,GO:0005579,GO:0005615,GO:0005886,GO:0006955,GO:0006956,GO:0006957,GO:0006958,GO:0016020,GO:0031640,GO:0044877,GO:0050778,GO:0070062,GO:1903561

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
C8B hsa:732 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
C8B hsa:732 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)
C8B hsa:732 path:hsa05020 Prion disease - Homo sapiens (human)
C8B hsa:732 path:hsa05146 Amoebiasis - Homo sapiens (human)
C8B hsa:732 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
C8B hsa:732 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 C8B 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 C8B 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 C8B 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA C8B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF C8B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A C8B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
C5 C8B 25361965 interaction type N/A PTMCode2
C8B C5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
C8A C8B 10387094 25348397 27898060 N/A in vitro,in vivo ComPPI,OmniPath
CLU C8B 25348397 N/A physical interaction,in vitro ComPPI
C5 C8B 25348397 N/A physical interaction,in vitro ComPPI

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