GENE：CLN8
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CLN8 |
| FullNmae | CLN8 transmembrane ER and ERGIC protein |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:2079 |
| EnsembleID | ENSG00000182372 |
| Uniprot | Q9UBY8 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CLN8 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CLN8 | GO:0005515,GO:0005739,GO:0005783,GO:0005783,GO:0005789,GO:0005793,GO:0006644,GO:0006644,GO:0006672,GO:0006869,GO:0007006,GO:0007040,GO:0007399,GO:0007399,GO:0007601,GO:0007628,GO:0008203,GO:0008306,GO:0008361,GO:0008610,GO:0016020,GO:0021523,GO:0030163,GO:0033116,GO:0035176,GO:0043524,GO:0045494,GO:0045861,GO:0046513,GO:0050881,GO:0050884,GO:0050885,GO:0051935,GO:0055088,GO:0060041,GO:0060052,GO:0097001,GO:0097001,GO:0097473,GO:0098793 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | CLN8 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | CLN8 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| ETS1 | CLN8 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | CLN8 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | CLN8 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | CLN8 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | CLN8 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | CLN8 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | CLN8 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | CLN8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CLN8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CLN8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CLN8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CLN8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CLN8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CLN8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | CLN8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | CLN8 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00005651EE | CLN8 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000DDD35 | CLN8 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000035CC3E | CLN8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000345DEB | CLN8 | 20371350 21572407 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A057E | CLN8 | 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000272039 | CLN8 | 20371350 21572407 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C85B2 | CLN8 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FC5B0 | CLN8 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B989F | CLN8 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A7F58 | CLN8 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | CLN8 | 22927820 23313552 23824327 25416803 27292025 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000058BB84 | CLN8 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D1FC | CLN8 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | CLN8 | 20371350 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000080D0A | CLN8 | 20371350 21572407 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000058276F | CLN8 | 20371350 21572407 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000166778 | CLN8 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C48FA | CLN8 | 22927820 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000148B91 | CLN8 | 22927820 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | CLN8 | 22927820 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B0B46 | CLN8 | 22927820 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000042935A | CLN8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F4AC3 | CLN8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AA464 | CLN8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00007455B8 | CLN8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000043D2C1 | CLN8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000008AA34 | CLN8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000118224 | CLN8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | CLN8 | 23313552 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5BAA | CLN8 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D5FFC | CLN8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000331800 | CLN8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B0920 | CLN8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003FD55 | CLN8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001067D1 | CLN8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000045DBD | CLN8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004AC389 | CLN8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016D2D4 | CLN8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EED18 | CLN8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000028DE3F | CLN8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000211070 | CLN8 | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000100748 | CLN8 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000032835F | CLN8 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AD002 | CLN8 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000075C4B1 | CLN8 | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TMEM11 | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| GABARAPL2 | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| CD9 | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| VAPA | CLN8 | 23142642 25348397 27898060 | N/A | physical interaction | ComPPI,OmniPath |
| PDIA6 | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| UBC | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| STX8 | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| RTN4 | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| PLP2 | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| PTPRN | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| BNIP3 | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| TUBB4A | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| MTX1 | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| NDRG2 | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| ERG28 | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| BNIP3L | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| RRP15 | CLN8 | 25348397 | N/A | physical interaction | ComPPI |
| FZD7 | CLN8 | 24234451 28298427 | physical association | ubiquitin reconstruction | IntAct |