Gene Information gene info

  1. Home

GENE：COPS4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol COPS4
FullNmae COP9 signalosome subunit 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16702
EnsembleID ENSG00000138663
Uniprot Q9BT78

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
COPS4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
COPS4 GO:0000338,GO:0000338,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0005829,GO:0008021,GO:0008180,GO:0008180,GO:0008180,GO:0008180,GO:0016607,GO:0019784,GO:0030054,GO:0045116,GO:2000434

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
COPS3 COPS4 23180781 9535219 physical association chromatography technology InnateDB
CUL1 COPS4 16036220 23180781 physical association anti tag coimmunoprecipitation InnateDB
COPS4 BRME1 16189514 23180781 physical association pull down InnateDB
IRF8 COPS4 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
NEDD8 COPS4 21145461 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 COPS4 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 COPS4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 COPS4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 COPS4 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 COPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF COPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 COPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 COPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS COPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A COPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 COPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000204177 COPS4 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS000013E79D COPS4 24374217 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
KPNA2 COPS4 25348397 N/A physical interaction ComPPI
CUL5 COPS4 11337588 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KRT19 COPS4 24234451 25348397 26871637 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KLHL42 COPS4 25348397 N/A physical interaction ComPPI
CEP43 COPS4 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
BAG3 COPS4 25348397 N/A physical interaction ComPPI
SKP1 COPS4 25348397 N/A physical interaction ComPPI
FBXO17 COPS4 25348397 N/A physical interaction ComPPI
DCUN1D1 COPS4 25348397 N/A physical interaction ComPPI
CCDC85B COPS4 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HSP90AB1 COPS4 25348397 N/A physical interaction ComPPI
ABRAXAS2 COPS4 19214193 24234451 25348397 association biochemical ComPPI,IntAct
JUN COPS4 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 COPS4 11285227 11337588 14525934 14647295 18850735 19615732 20399188 24234451 25348397 9707402 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo,tandem affinity purification,inference by socio-affinity scoring ComPPI,HPRD,IntAct
COP1 COPS4 25348397 N/A physical interaction ComPPI
IRF8 COPS4 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBX1 COPS4 25348397 N/A physical interaction ComPPI
CUL3 COPS4 25348397 N/A physical interaction ComPPI
YWHAZ COPS4 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
UBC COPS4 25348397 N/A physical interaction ComPPI
DLD COPS4 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
NTRK1 COPS4 25348397 N/A physical interaction ComPPI
BTRC COPS4 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ENAH COPS4 25348397 N/A physical interaction ComPPI
STIP1 COPS4 25348397 N/A physical interaction ComPPI
IKBKB COPS4 25348397 N/A physical interaction ComPPI
CSNK2A1 COPS4 25348397 N/A physical interaction ComPPI
PRMT5 COPS4 25348397 N/A physical interaction ComPPI
SYT1 COPS4 21102408 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
GRK5 COPS4 25348397 N/A physical interaction ComPPI
YWHAQ COPS4 25348397 N/A physical interaction ComPPI
COPS2 COPS4 11285227 11337588 14525934 14647295 24234451 25043011 25348397 9707402 physical association experimental interaction detection,molecular sieving,x-ray crystallography,physical interaction,in vitro,in vivo,inference by socio-affinity scoring ComPPI,HPRD,IntAct
ARF6 COPS4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
NEDD8 COPS4 25348397 N/A physical interaction ComPPI
CUL2 COPS4 25348397 N/A physical interaction ComPPI
CUL4B COPS4 23238014 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SNAPIN COPS4 25348397 N/A physical interaction ComPPI
WDR77 COPS4 25348397 N/A physical interaction ComPPI
EPB41L1 COPS4 25348397 N/A physical interaction ComPPI
EPB41L2 COPS4 25348397 N/A physical interaction ComPPI
CUL1 COPS4 25348397 N/A physical interaction ComPPI
CUL4A COPS4 25348397 N/A physical interaction ComPPI
STON2 COPS4 25348397 N/A physical interaction ComPPI
STK11 COPS4 24234451 25348397 25852190 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS3 COPS4 11285227 11337588 14525934 14647295 20399188 24234451 25043011 25348397 9707402 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
COPS4 COPS6 11285227 11337588 14525934 14647295 19615732 24234451 25043011 25348397 9707402 association,physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach,inference by socio-affinity scoring ComPPI,HPRD,IntAct
COPS4 COPS7A 11285227 11337588 14525934 14647295 24234451 25348397 26496610 9707402 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
COPS4 COPS8 11285227 11337588 14525934 14647295 24234451 25043011 25348397 27173435 9707402 association,physical association experimental interaction detection,pull down,physical interaction,in vitro,in vivo,tandem affinity purification,inference by socio-affinity scoring ComPPI,HPRD,IntAct
COPS4 RCBTB2 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
COPS4 MBIP 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
COPS4 BRME1 14525934 16189514 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid ComPPI,HPRD,IntAct
COPS4 USHBP1 14525934 16189514 24234451 25348397 25416956 26871637 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
COPS4 WRAP73 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS4 KLHL13 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS4 DDB1 25348397 N/A physical interaction ComPPI
COPS4 GPS1 20399188 24234451 25348397 27029275 physical association transmission electron microscopy,electron microscopy,molecular sieving,x-ray crystallography,physical interaction,electron tomography ComPPI,IntAct
COPS4 DDB2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS4 ERCC8 25348397 N/A physical interaction ComPPI
COPS4 DCAF1 25348397 N/A physical interaction ComPPI
COPS4 PTPN14 25348397 N/A physical interaction ComPPI
COPS4 TOR1A 21102408 24234451 25348397 colocalization physical interaction,fluorescence microscopy ComPPI,IntAct
COPS4 ERCC6 25348397 N/A physical interaction ComPPI
COPS4 ERCC6 25348397 N/A physical interaction ComPPI
COPS4 LRR1 25348397 N/A physical interaction ComPPI
COPS4 COPS7B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
COPS4 SARS2 25348397 N/A physical interaction ComPPI
COPS4 ELOB 25348397 N/A physical interaction ComPPI
COPS4 ELOC 25348397 N/A physical interaction ComPPI
COPS4 FEM1B 25348397 N/A physical interaction ComPPI
COPS4 LRRC14 25348397 N/A physical interaction ComPPI
COPS4 BTBD1 25348397 N/A physical interaction ComPPI
COPS4 BTBD2 25348397 N/A physical interaction ComPPI
COPS4 KLHL18 25348397 N/A physical interaction ComPPI
COPS4 DCAF11 25348397 N/A physical interaction ComPPI
COPS4 DTL 25348397 N/A physical interaction ComPPI
COPS4 CRBN 24234451 25348397 27029275 physical association transmission electron microscopy,physical interaction ComPPI,IntAct
COPS4 TOR1AIP2 25348397 N/A physical interaction ComPPI
COPS4 TOR1AIP2 25348397 N/A physical interaction ComPPI
COPS4 IRF5 25348397 N/A physical interaction ComPPI
COPS4 FBXW4 25348397 N/A physical interaction ComPPI
COPS4 FOS 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
COPS4 FBXO6 25348397 N/A physical interaction ComPPI
COPS4 CAST 25348397 N/A physical interaction ComPPI
COPS4 DCAF8 25348397 N/A physical interaction ComPPI
COPS4 MOV10 25348397 N/A physical interaction ComPPI
COPS4 NXF1 25348397 N/A physical interaction ComPPI
COPS4 GUCY1A1 25348397 N/A physical interaction ComPPI
COPS4 TP53 11285227 14525934 22653443 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction ComPPI,HPRD,IntAct
COPS4 EIF3M 25348397 N/A physical interaction ComPPI
COPS4 IBTK 25348397 N/A physical interaction ComPPI
COPS4 HEMGN 25348397 N/A physical interaction ComPPI
COPS4 APBB3 25348397 N/A physical interaction ComPPI
COPS4 DET1 25348397 N/A physical interaction ComPPI
COPS4 UBE2M 25348397 N/A physical interaction ComPPI
COPS4 FBXO7 25348397 N/A physical interaction ComPPI
COPS4 KLHL10 25348397 N/A physical interaction ComPPI
COPS4 DCAF4 25348397 N/A physical interaction ComPPI
COPS4 DENR 25348397 N/A physical interaction ComPPI
COPS4 DCAF4L2 25348397 N/A physical interaction ComPPI
COPS4 SIRT7 25348397 N/A physical interaction ComPPI
COPS4 FBXW5 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
COPS4 PCDHB12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COPS4 PEX14 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COPS4 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
DDA1 COPS4 25348397 N/A physical interaction ComPPI
COPS4 COPS4 12615944 14525934 N/A two hybrid HPRD

Visualization










  Return