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GENE：CRTAM

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CRTAM
FullNmae cytotoxic and regulatory T cell molecule
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24313
EnsembleID ENSG00000109943
Uniprot O95727

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CRTAM immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CRTAM GO:0001768,GO:0001772,GO:0001819,GO:0002355,GO:0002355,GO:0002860,GO:0002860,GO:0005102,GO:0005102,GO:0005886,GO:0005886,GO:0005886,GO:0007157,GO:0008037,GO:0008037,GO:0032729,GO:0045580,GO:0045954,GO:0046007,GO:0050863,GO:0051606,GO:0097021,GO:2001185

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CRTAM SCRIB 15811952 22285893 26192618 26694968 association N/A ACSN
CRTAM IFNG 15811952 22285893 26192618 26694968 interaction type N/A ACSN
CADM1 CRTAM 15811952 22285893 26192618 interaction type N/A ACSN
CD4 CRTAM 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 26192618 3263576 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
LCK CRTAM 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 26192618 3263576 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
CRTAM TLN1 15811952 22285893 26192618 26694968 interaction type N/A ACSN
NFKB1 CRTAM 12947093 23180781 physical association electrophoretic mobility shift assay InnateDB
EGR1 CRTAM 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 CRTAM 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CRTAM 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 CRTAM 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CRTAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CRTAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CRTAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 CRTAM 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 CRTAM 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 CRTAM 19088304 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
CRTAM SCRIB 25361965 interaction type N/A PTMCode2
SCRIB CRTAM 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CADM1 CRTAM 23871486 25348397 27898060 N/A cosedimentation in solution,molecular sieving,x-ray crystallography,physical interaction,surface plasmon resonance array ComPPI,OmniPath

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