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GENE：DAPP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DAPP1
FullNmae dual adaptor of phosphotyrosine and 3-phosphoinositides 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16500
EnsembleID ENSG00000070190
Uniprot Q9UN19

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DAPP1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DAPP1 GO:0005515,GO:0005543,GO:0005547,GO:0005829,GO:0005886,GO:0005886,GO:0006470,GO:0007165,GO:0043325

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DAPP1 hsa:27071 path:hsa04662 B cell receptor signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PLCG2 DAPP1 10770799 29145629 physical association inferred by curator Reactome

Source Target Pmid Interactiontype Methods Database
GATA1 DAPP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 DAPP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 DAPP1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C DAPP1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 DAPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DAPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DAPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DAPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DAPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DAPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DAPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DAPP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SRC DAPP1 22135298 phosphorylation N/A PhosphoSite
LCK DAPP1 22135298 phosphorylation N/A PhosphoSite
LYN DAPP1 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
ZNHIT1 DAPP1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
BTK DAPP1 11524430 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LYN DAPP1 11524430 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SRC DAPP1 11524430 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
LCK DAPP1 10880360 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PLCG2 DAPP1 25348397 N/A in vitro,in vivo ComPPI
MAP4K1 DAPP1 14525934 14563325 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
HSPA1A DAPP1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
HSPA1B DAPP1 25348397 N/A two hybrid,physical interaction ComPPI
TNFAIP1 DAPP1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
FXN DAPP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FCHSD2 DAPP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH2D1B DAPP1 23322602 24234451 25348397 association pull down ComPPI,IntAct
RPL23 DAPP1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
CNDP2 DAPP1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MYLIP DAPP1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
DAPP1 ERBB3 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
DAPP1 HSD3B7 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DAPP1 GSTCD 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,validated two hybrid ComPPI,IntAct
DAPP1 WDR20 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping,validated two hybrid ComPPI,IntAct
DAPP1 MGARP 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DAPP1 RBP7 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DAPP1 TM4SF19 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DAPP1 APBB3 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array,luminescence based mammalian interactome mapping ComPPI,IntAct
DAPP1 PLAGL2 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DAPP1 LRRK2 24234451 24947832 25348397 N/A protein array ComPPI,IntAct
PLCG1 DAPP1 10770799 14525934 N/A experimental interaction detection HPRD
SRC DAPP1 10770799 10880360 11102801 11524430 15494510 17389395 19901323 27898060 stimulant N/A OmniPath
LCK DAPP1 10880360 17389395 19901323 27898060 stimulant N/A OmniPath
LYN DAPP1 10880360 11524430 17389395 19901323 27898060 stimulant N/A OmniPath
BTK DAPP1 10880360 11524430 17389395 19901323 27898060 N/A N/A OmniPath

Visualization










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