Gene Information gene info

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GENE：DDX18

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DDX18
FullNmae DEAD-box helicase 18
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2741
EnsembleID ENSG00000088205
Uniprot Q9NVP1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DDX18 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DDX18 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DDX18 GO:0000463,GO:0003723,GO:0003724,GO:0005515,GO:0005524,GO:0005694,GO:0005730,GO:0005730,GO:0016020,GO:0016887

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SUZ12 DDX18 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 DDX18 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
APP DDX18 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 DDX18 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 DDX18 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A DDX18 18971253 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
MYC DDX18 12747840 8861962 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 DDX18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DDX18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DDX18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DDX18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DDX18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DDX18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DDX18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 DDX18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 DDX18 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 DDX18 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000005481D DDX18 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000157026 DDX18 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000031E12 DDX18 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 DDX18 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
DDX18 DKC1 25361965 interaction type N/A PTMCode2
DKC1 DDX18 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
BYSL DDX18 25348397 N/A physical interaction ComPPI
DHX15 DDX18 25348397 N/A physical interaction ComPPI
RPL9 DDX18 25348397 N/A physical interaction ComPPI
RPS7 DDX18 25348397 N/A physical interaction ComPPI
LMNA DDX18 25348397 N/A physical interaction ComPPI
RPL11 DDX18 25348397 N/A physical interaction ComPPI
KEAP1 DDX18 25348397 N/A physical interaction ComPPI
NIFK DDX18 25348397 N/A physical interaction ComPPI
GLYR1 DDX18 25348397 N/A physical interaction ComPPI
TBL3 DDX18 25348397 N/A physical interaction ComPPI
RRS1 DDX18 25348397 N/A physical interaction ComPPI
RPL10 DDX18 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FGF3 DDX18 25348397 N/A physical interaction ComPPI
JUN DDX18 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 DDX18 25348397 N/A physical interaction ComPPI
RPL18A DDX18 25348397 N/A physical interaction ComPPI
PAXIP1 DDX18 25348397 N/A physical interaction ComPPI
CUL3 DDX18 25348397 N/A physical interaction ComPPI
POLR1E DDX18 25348397 N/A physical interaction ComPPI
UBC DDX18 25348397 N/A physical interaction ComPPI
NTRK1 DDX18 25348397 N/A physical interaction ComPPI
CANX DDX18 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PRPF40A DDX18 25348397 N/A physical interaction ComPPI
HNRNPU DDX18 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DDX5 DDX18 25348397 N/A physical interaction ComPPI
BCCIP DDX18 25348397 N/A physical interaction ComPPI
ABCE1 DDX18 25348397 N/A physical interaction ComPPI
RPS6 DDX18 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CUL1 DDX18 25348397 N/A physical interaction ComPPI
H1-4 DDX18 25348397 N/A physical interaction ComPPI
RPL7A DDX18 25348397 N/A physical interaction ComPPI
RAB11A DDX18 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PINX1 DDX18 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RNF2 DDX18 25348397 N/A physical interaction ComPPI
MTA1 DDX18 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
VCAM1 DDX18 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
EED DDX18 25348397 N/A physical interaction ComPPI
CRMP1 DDX18 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UTP14A DDX18 25348397 N/A physical interaction ComPPI
RAB9A DDX18 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CUL7 DDX18 25348397 N/A physical interaction ComPPI
H3C1 DDX18 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CAND1 DDX18 25348397 N/A physical interaction ComPPI
PRPF6 DDX18 25348397 N/A physical interaction ComPPI
SRSF3 DDX18 25348397 N/A physical interaction ComPPI
RPL5 DDX18 25348397 N/A physical interaction ComPPI
HNRNPR DDX18 25348397 N/A physical interaction ComPPI
GAR1 DDX18 25348397 N/A physical interaction ComPPI
ELAVL1 DDX18 25348397 N/A physical interaction ComPPI
NOP56 DDX18 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ILF2 DDX18 25348397 N/A physical interaction ComPPI
ESR1 DDX18 21182205 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
SNU13 DDX18 25348397 N/A physical interaction ComPPI
RPL23 DDX18 25348397 N/A physical interaction ComPPI
PATJ DDX18 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
TGOLN2 DDX18 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AURKAIP1 DDX18 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
AURKB DDX18 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BET1 DDX18 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
IFI16 DDX18 25348397 N/A physical interaction ComPPI
PES1 DDX18 25348397 N/A physical interaction ComPPI
AGO1 DDX18 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RRP1B DDX18 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
POLR1B DDX18 25348397 N/A physical interaction ComPPI
SUZ12 DDX18 25348397 N/A physical interaction ComPPI
EZR DDX18 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
POLR1D DDX18 25348397 N/A physical interaction ComPPI
POLR1D DDX18 25348397 N/A physical interaction ComPPI
DGCR8 DDX18 25348397 N/A physical interaction ComPPI
MPHOSPH10 DDX18 25348397 N/A physical interaction ComPPI
NIP7 DDX18 25348397 N/A physical interaction ComPPI
DDX56 DDX18 25348397 N/A physical interaction ComPPI
PWP1 DDX18 25348397 N/A physical interaction ComPPI
RPS2 DDX18 25348397 N/A physical interaction ComPPI
RPS14 DDX18 25348397 N/A physical interaction ComPPI
RPS15A DDX18 25348397 N/A physical interaction ComPPI
KRR1 DDX18 25348397 N/A physical interaction ComPPI
RPL8 DDX18 25348397 N/A physical interaction ComPPI
DKC1 DDX18 25348397 N/A physical interaction ComPPI
MTF1 DDX18 25348397 N/A physical interaction ComPPI
DDX24 DDX18 25348397 N/A physical interaction ComPPI
RPL36 DDX18 25348397 N/A physical interaction ComPPI
NOC2L DDX18 25348397 N/A physical interaction ComPPI
FBL DDX18 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FGF8 DDX18 25348397 N/A physical interaction ComPPI
DPF2 DDX18 25348397 N/A physical interaction ComPPI
GTPBP4 DDX18 25348397 N/A physical interaction ComPPI
MNDA DDX18 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
BRIX1 DDX18 25348397 N/A physical interaction ComPPI
RPS4X DDX18 25348397 N/A physical interaction ComPPI
SURF2 DDX18 25348397 N/A physical interaction ComPPI
SIRT7 DDX18 25348397 N/A physical interaction ComPPI
PWP2 DDX18 25348397 N/A physical interaction ComPPI
DDX18 APP 25348397 N/A physical interaction ComPPI
DDX18 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
DDX18 FBXO6 25348397 N/A physical interaction ComPPI
DDX18 OBSL1 25348397 N/A physical interaction ComPPI
DDX18 ZBTB38 25348397 N/A physical interaction ComPPI
DDX18 ABCF2 25348397 N/A physical interaction ComPPI
DDX18 DCAF13 25348397 N/A physical interaction ComPPI
DDX18 PUM3 25348397 N/A physical interaction ComPPI
DDX18 DDX47 25348397 N/A physical interaction ComPPI
DDX18 DDX55 25348397 N/A physical interaction ComPPI
DDX18 ESF1 25348397 N/A physical interaction ComPPI
DDX18 GNL1 25348397 N/A physical interaction ComPPI
DDX18 GRWD1 25348397 N/A physical interaction ComPPI
DDX18 NAT10 25348397 N/A physical interaction ComPPI
DDX18 NEMF 25348397 N/A physical interaction ComPPI
DDX18 NOL10 25348397 N/A physical interaction ComPPI
DDX18 NOL6 25348397 N/A physical interaction ComPPI
DDX18 NOP2 25348397 N/A physical interaction ComPPI
DDX18 NOP58 25348397 N/A physical interaction ComPPI
DDX18 NSA2 25348397 N/A physical interaction ComPPI
DDX18 POLR1C 25348397 N/A physical interaction ComPPI
DDX18 RBM28 25348397 N/A physical interaction ComPPI
DDX18 RPF2 25348397 N/A physical interaction ComPPI
DDX18 RPL27 25348397 N/A physical interaction ComPPI
DDX18 RRP15 25348397 N/A physical interaction ComPPI
DDX18 TSR1 25348397 N/A physical interaction ComPPI
DDX18 UTP20 25348397 N/A physical interaction ComPPI
DDX18 WDR3 25348397 N/A physical interaction ComPPI
DDX18 WDR36 25348397 N/A physical interaction ComPPI
DDX18 KMT2E 25348397 N/A physical interaction ComPPI
DDX18 C1ORF131 25348397 N/A physical interaction ComPPI
DDX18 MACROH2A2 25348397 N/A physical interaction ComPPI
DDX18 RPL18 25348397 N/A physical interaction ComPPI
DDX18 NCL 25348397 N/A physical interaction ComPPI
EBNA1BP2 DDX18 25348397 N/A physical interaction ComPPI
HSCB DDX18 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
DDX18 RPL29 24234451 30021884 physical association cross-linking study IntAct
DDX18 GNL3 24234451 30021884 physical association cross-linking study IntAct

Visualization










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