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GENE：ELMO2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ELMO2
FullNmae engulfment and cell motility 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17233
EnsembleID ENSG00000062598
Uniprot Q96JJ3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ELMO2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ELMO2 GO:0005515,GO:0005829,GO:0005829,GO:0006909,GO:0006915,GO:0007015,GO:0016020,GO:0017124,GO:0030971,GO:0048870,GO:0060326

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ELMO2 hsa:63916 path:hsa05100 Bacterial invasion of epithelial cells - Homo sapiens (human)
ELMO2 hsa:63916 path:hsa05131 Shigellosis - Homo sapiens (human)
ELMO2 hsa:63916 path:hsa05132 Salmonella infection - Homo sapiens (human)
ELMO2 hsa:63916 path:hsa05135 Yersinia infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ELMO2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ELMO2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ELMO2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ELMO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ELMO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ELMO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ELMO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ELMO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 ELMO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HIF1A ELMO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ELMO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ELMO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ELMO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ELMO2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003E1A9 ELMO2 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000008DA94 ELMO2 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000012A1DD ELMO2 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS0000171525 ELMO2 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000055BBE5 ELMO2 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS00000AA464 ELMO2 20304954 22473208 25416803 mrna cleavage,inhibition array technology,clip TarBase
URS000055BBE5 ELMO2 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000008DA94 ELMO2 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000171525 ELMO2 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003E1A9 ELMO2 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000012A1DD ELMO2 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00002075FA ELMO2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000367985 ELMO2 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
AXL ELMO2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
ARL4A ELMO2 25348397 N/A physical interaction ComPPI
NPM1 ELMO2 25348397 N/A physical interaction ComPPI
RHOG ELMO2 25348397 N/A in vitro,in vivo ComPPI
CRKL ELMO2 25348397 N/A physical interaction ComPPI
GRB2 ELMO2 21706016 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BTRC ELMO2 25348397 N/A physical interaction ComPPI
CEP135 ELMO2 25348397 N/A physical interaction ComPPI
DOCK1 ELMO2 25348397 N/A two hybrid,in vitro ComPPI
ELMO1 ELMO2 25348397 N/A physical interaction ComPPI
ELMO2 FBXW11 25348397 N/A physical interaction ComPPI
ELMO2 MLH1 25348397 N/A physical interaction ComPPI
ELMO2 CDC27 25348397 N/A physical interaction ComPPI
ELMO2 DOCK5 25348397 N/A physical interaction ComPPI
ELMO2 ELMO3 25348397 N/A physical interaction ComPPI
ELMO2 RAC2 25348397 N/A physical interaction ComPPI
ELMO2 ERMAP 25348397 N/A physical interaction ComPPI
ELMO2 EPHA1 25348397 N/A physical interaction ComPPI
ELMO2 ARRB1 25348397 N/A physical interaction ComPPI

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