GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
EMC8 |
| FullNmae |
ER membrane protein complex subunit 8 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:7864 |
| EnsembleID |
ENSG00000131148 |
| Uniprot |
O43402 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| EMC8 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| EMC8 |
GO:0005515,GO:0005737,GO:0005783,GO:0005789,GO:0005794,GO:0016020,GO:0032977,GO:0045050,GO:0045050,GO:0071816,GO:0072546,GO:0072546,GO:0072546 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| CEBPA |
EMC8 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
EMC8 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
EMC8 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
EMC8 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| HNF4A |
EMC8 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| MITF |
EMC8 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| TAL1 |
EMC8 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS00005651EE |
EMC8 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS0000215483 |
EMC8 |
20371350
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000039A052 |
EMC8 |
23313552
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000134ADC |
EMC8 |
23313552
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000070B1D |
EMC8 |
23313552
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000044FD7 |
EMC8 |
23313552
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00002B0B46 |
EMC8 |
23313552
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000003575B |
EMC8 |
23313552
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00000821E0 |
EMC8 |
23313552
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| KRT6A |
EMC8 |
25348397
|
N/A |
physical interaction |
ComPPI |
| EMC2 |
EMC8 |
14525934
16189514
24234451
25348397
26496610
30021884
|
association,physical association |
anti tag coimmunoprecipitation,cross-linking study,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid |
ComPPI,HPRD,IntAct |
| CANX |
EMC8 |
24234451
25348397
29568061
|
association |
proximity-dependent biotin identification |
ComPPI,IntAct |
| UBQLN2 |
EMC8 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TRIM25 |
EMC8 |
25348397
|
N/A |
physical interaction |
ComPPI |
| BCL7A |
EMC8 |
25348397
|
N/A |
physical interaction |
ComPPI |
| LPAR1 |
EMC8 |
25348397
|
N/A |
physical interaction |
ComPPI |
| APP |
EMC8 |
25348397
|
N/A |
physical interaction |
ComPPI |
| EMC8 |
MOV10 |
25348397
|
N/A |
physical interaction |
ComPPI |
| EMC8 |
NXF1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| EMC8 |
SLC18A1 |
25348397
|
N/A |
physical interaction |
ComPPI |
| EMC8 |
NDUFA9 |
24234451
24344204
25348397
|
association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| EMC8 |
PNO1 |
25144938
27898060
|
N/A |
N/A |
OmniPath |
| EMC8 |
NOP14 |
12446671
20019888
27898060
|
N/A |
N/A |
OmniPath |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS00009BC8B8 |
EMC8 |
27087310
|
direct interaction,inhibition |
N/A |
NPInter |
Visualization