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GENE：EXOSC7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EXOSC7
FullNmae exosome component 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28112
EnsembleID ENSG00000075914
Uniprot Q15024

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EXOSC7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EXOSC7 GO:0000175,GO:0000176,GO:0000176,GO:0000177,GO:0000177,GO:0000178,GO:0000178,GO:0000178,GO:0000467,GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0005730,GO:0005829,GO:0005829,GO:0006364,GO:0006396,GO:0006401,GO:0006401,GO:0034427,GO:0034473,GO:0034475,GO:0034476,GO:0043928,GO:0071028,GO:0071035,GO:0071038,GO:0071042,GO:0101019

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EXOSC7 hsa:23016 path:hsa03018 RNA degradation - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR EXOSC7 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 EXOSC7 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 EXOSC7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 EXOSC7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 EXOSC7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 EXOSC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EXOSC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EXOSC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EXOSC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 EXOSC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR EXOSC7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
EXOSC5 EXOSC7 25361965 interaction type N/A PTMCode2
EXOSC7 EXOSC5 25361965 interaction type N/A PTMCode2
EXOSC7 EXOSC2 25361965 interaction type N/A PTMCode2
EXOSC2 EXOSC7 25361965 interaction type N/A PTMCode2
EXOSC7 EXOSC9 25361965 interaction type N/A PTMCode2
EXOSC9 EXOSC7 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
EXOSC5 EXOSC7 11719186 14525934 24234451 25348397 26496610 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
TSNAX EXOSC7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOSC1 EXOSC7 11719186 11812149 12419256 12788944 14525934 24234451 25043052 25348397 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,molecular sieving,pull down,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
EXOSC8 EXOSC7 11719186 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
JUN EXOSC7 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RPA1 EXOSC7 25348397 N/A physical interaction ComPPI
GDI1 EXOSC7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPA2 EXOSC7 25348397 N/A physical interaction ComPPI
RPA3 EXOSC7 25348397 N/A physical interaction ComPPI
EXOSC10 EXOSC7 11812149 14525934 15231747 21255825 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
MTREX EXOSC7 11719186 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
EXOSC6 EXOSC7 11719186 12419256 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
AICDA EXOSC7 21255825 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
UBE2K EXOSC7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EXOSC4 EXOSC7 11719186 12419256 14525934 20531386 24234451 25348397 25416956 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,mammalian protein protein interaction trap,in vivo,inference by socio-affinity scoring ComPPI,HPRD,IntAct
DHPS EXOSC7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SLIT2 EXOSC7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LUM EXOSC7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
C1D EXOSC7 25348397 N/A physical interaction ComPPI
PALS2 EXOSC7 11719186 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MPHOSPH6 EXOSC7 25348397 N/A physical interaction ComPPI
DXO EXOSC7 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
GIGYF2 EXOSC7 25348397 N/A physical interaction ComPPI
HECW2 EXOSC7 25348397 N/A physical interaction ComPPI
DIS3 EXOSC7 11719186 14525934 20531386 24234451 25348397 association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
EXOSC2 EXOSC7 11719186 12419256 14525934 15231747 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
EXOSC9 EXOSC7 12788944 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,in vivo,inference by socio-affinity scoring ComPPI,IntAct
EXOSC7 IP6K1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
EXOSC7 DIS3L 20531386 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
EXOSC7 EXOSC3 20531389 21255825 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOSC7 APP 25348397 N/A physical interaction ComPPI
EXOSC7 TP53 25348397 N/A physical interaction ComPPI
EXOSC7 RBM7 25348397 N/A physical interaction ComPPI
EXOSC7 HBS1L 25348397 N/A physical interaction ComPPI
EXOSC7 ZCCHC8 25348397 N/A physical interaction ComPPI
EXOSC7 ZFC3H1 25348397 N/A physical interaction ComPPI
EXOSC7 USP30 25348397 N/A physical interaction ComPPI
EXOSC7 IFI16 25348397 N/A physical interaction ComPPI
EXOSC7 HDAC1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOSC7 MRPL50 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOSC7 MZT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOSC7 RSRC1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOSC7 LRRC47 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EXOSC7 ZC3HAV1 21876179 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
EXOSC7 MTMR3 12419256 24234451 25348397 physical association two hybrid ComPPI,IntAct
EXOSC7 UBE2Q1 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
EXOSC7 UBE2Q2 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
EXOSC7 MNDA 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
EXOSC7 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
NUDCD1 EXOSC7 24234451 29021621 association anti tag coimmunoprecipitation IntAct
MKI67 EXOSC7 24234451 26949251 association anti tag coimmunoprecipitation IntAct

Visualization










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