GENE：FAM114A1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | FAM114A1 |
| FullNmae | family with sequence similarity 114 member A1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:25087 |
| EnsembleID | ENSG00000197712 |
| Uniprot | Q8IWE2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| FAM114A1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| FAM114A1 | GO:0005515,GO:0005654,GO:0005794,GO:0005829 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | FAM114A1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ESR1 | FAM114A1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | FAM114A1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA3 | FAM114A1 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXA1 | FAM114A1 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | FAM114A1 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | FAM114A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | FAM114A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | FAM114A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | FAM114A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | FAM114A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | FAM114A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | FAM114A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | FAM114A1 | 18185580 20371350 25416803 | mrna cleavage,inhibition | array technology,clip | TarBase |
| URS00001496AE | FAM114A1 | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B59A2 | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000039E1E1 | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000048BA36 | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000031602A | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000251D0B | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C11BC | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C0FCB | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000315338 | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E949 | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000027080C | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000346991 | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000070CD2 | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000037D7E5 | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003883FE | FAM114A1 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| FAF1 | FAM114A1 | 25348397 | N/A | physical interaction | ComPPI |
| TLN1 | FAM114A1 | 25348397 | N/A | physical interaction | ComPPI |
| TNS2 | FAM114A1 | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| AGTRAP | FAM114A1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| RAB2A | FAM114A1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| SNAPIN | FAM114A1 | 23414517 24234451 25348397 | physical association | two hybrid fragment pooling approach | ComPPI,IntAct |
| SPG21 | FAM114A1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| HSPA4 | FAM114A1 | 25348397 | N/A | physical interaction | ComPPI |
| TNFRSF10D | FAM114A1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| RSU1 | FAM114A1 | 25348397 | N/A | physical interaction | ComPPI |
| AKT1S1 | FAM114A1 | 25348397 | N/A | physical interaction | ComPPI |
| TARS1 | FAM114A1 | 25348397 | N/A | physical interaction | ComPPI |
| N4BP1 | FAM114A1 | 25348397 | N/A | physical interaction | ComPPI |
| GDAP1 | FAM114A1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| FAM114A1 | CMTM5 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |