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GENE：GRHPR

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GRHPR
FullNmae glyoxylate and hydroxypyruvate reductase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4570
EnsembleID ENSG00000137106
Uniprot Q9UBQ7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GRHPR immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GRHPR GO:0005515,GO:0005737,GO:0005782,GO:0005829,GO:0008465,GO:0008465,GO:0016618,GO:0016618,GO:0019752,GO:0030267,GO:0030267,GO:0030267,GO:0031406,GO:0042803,GO:0043648,GO:0046487,GO:0051287,GO:0070062,GO:0070402,GO:1902494

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GRHPR hsa:9380 path:hsa00260 Glycine, serine and threonine metabolism - Homo sapiens (human)
GRHPR hsa:9380 path:hsa00620 Pyruvate metabolism - Homo sapiens (human)
GRHPR hsa:9380 path:hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human)
GRHPR hsa:9380 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GRHPR POLR2F 23180781 23994473 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GRHPR 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 GRHPR 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 GRHPR 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA GRHPR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GRHPR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GRHPR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GRHPR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GRHPR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GRHPR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GRHPR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 GRHPR 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000079D48 GRHPR 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 GRHPR 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PCBP1 GRHPR 25348397 N/A physical interaction ComPPI
LSM1 GRHPR 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
KEAP1 GRHPR 25348397 N/A physical interaction ComPPI
LIG4 GRHPR 25348397 N/A physical interaction ComPPI
PTH2R GRHPR 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ACOX1 GRHPR 25348397 N/A physical interaction ComPPI
CTSD GRHPR 25348397 N/A physical interaction ComPPI
PGM1 GRHPR 25348397 N/A physical interaction ComPPI
PIR GRHPR 25348397 N/A physical interaction ComPPI
AKR1B1 GRHPR 25348397 N/A physical interaction ComPPI
RTN4 GRHPR 25348397 N/A physical interaction ComPPI
PRDX6 GRHPR 25348397 N/A physical interaction ComPPI
SUCLA2 GRHPR 25348397 N/A physical interaction ComPPI
HSPE1 GRHPR 25348397 N/A physical interaction ComPPI
CDC7 GRHPR 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GFER GRHPR 25348397 N/A physical interaction ComPPI
GLS2 GRHPR 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GRHPR HSD17B4 25348397 N/A physical interaction ComPPI
GRHPR SLC25A5 25348397 N/A physical interaction ComPPI
GRHPR CXADR 25348397 N/A physical interaction ComPPI
GRHPR FOS 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GRHPR MOV10 25348397 N/A physical interaction ComPPI
GRHPR NXF1 25348397 N/A physical interaction ComPPI
GRHPR ETFA 25348397 N/A physical interaction ComPPI
GRHPR ETFB 25348397 N/A physical interaction ComPPI
GRHPR AGL 25348397 N/A physical interaction ComPPI
GRHPR AKR1A1 25348397 N/A physical interaction ComPPI
GRHPR NAXD 25348397 N/A physical interaction ComPPI
GRHPR GLO1 25348397 N/A physical interaction ComPPI
GRHPR RFK 25348397 N/A physical interaction ComPPI
GRHPR VPS29 25348397 N/A physical interaction ComPPI
GRHPR TJP1 25348397 N/A physical interaction ComPPI
GRHPR UFM1 25348397 N/A physical interaction ComPPI

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