Gene Information gene info

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GENE：GSDMA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GSDMA
FullNmae gasdermin A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13311
EnsembleID ENSG00000167914
Uniprot Q96QA5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GSDMA pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GSDMA pyroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
GSDMA immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GSDMA GO:0001786,GO:0005515,GO:0005546,GO:0005829,GO:0005886,GO:0016020,GO:0022829,GO:0042742,GO:0042742,GO:0048471,GO:0055085,GO:0070269,GO:0070269,GO:0070273

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SUZ12 GSDMA 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR GSDMA 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 GSDMA 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 GSDMA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GSDMA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GSDMA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GSDMA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GSDMA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 GSDMA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001FC26E GSDMA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 GSDMA 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TBC1D22B GSDMA 25348397 N/A physical interaction ComPPI
MCM2 GSDMA 25348397 N/A physical interaction ComPPI
ZIC1 GSDMA 25348397 N/A physical interaction ComPPI
CFTR GSDMA 25348397 N/A physical interaction ComPPI
PRKN GSDMA 25348397 N/A physical interaction ComPPI
FOXH1 GSDMA 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
DDX19B GSDMA 25348397 N/A physical interaction ComPPI
IFI16 GSDMA 25348397 N/A physical interaction ComPPI
CEP152 GSDMA 25348397 N/A physical interaction ComPPI
SUZ12 GSDMA 25348397 N/A physical interaction ComPPI
CYLD GSDMA 25348397 N/A physical interaction ComPPI

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