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GENE：HCN3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HCN3
FullNmae hyperpolarization activated cyclic nucleotide gated potassium channel 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19183
EnsembleID ENSG00000143630
Uniprot Q9P1Z3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HCN3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HCN3 GO:0003254,GO:0005248,GO:0005249,GO:0005249,GO:0005515,GO:0005886,GO:0005886,GO:0030424,GO:0030425,GO:0030552,GO:0034765,GO:0035725,GO:0035725,GO:0042391,GO:0043025,GO:0044316,GO:0071805,GO:0071805,GO:0098855,GO:1903351

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HCN3 hsa:57657 path:hsa04929 GnRH secretion - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 HCN3 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HCN3 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 HCN3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CTCF HCN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HCN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HCN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000B59A2 HCN3 19074876 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
ELAVL1 HCN3 25348397 N/A physical interaction ComPPI
HCN4 HCN3 25348397 N/A physical interaction ComPPI

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