GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
HERC6 |
| FullNmae |
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:26072 |
| EnsembleID |
ENSG00000138642 |
| Uniprot |
Q8IVU3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| HERC6 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| HERC6 |
GO:0002244,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0006511,GO:0009617,GO:0016567,GO:0016567,GO:0061630 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| HERC6 |
HERC3 |
18535780
23180781
|
physical association |
anti tag coimmunoprecipitation |
InnateDB |
| HERC6 |
POLR2F |
23180781
23994473
|
physical association |
anti tag coimmunoprecipitation |
InnateDB |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| YBX1 |
HERC6 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| PRDM14 |
HERC6 |
18971253
20953172
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| CEBPA |
HERC6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
HERC6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F1 |
HERC6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
HERC6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
HERC6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
HERC6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| SPI1 |
HERC6 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS0000171CD1 |
HERC6 |
18362358
|
rna interference,inhibition |
array technology |
miRSponge |
| URS0000171CD1 |
HERC6 |
18362358
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| HSP90AB1 |
HERC6 |
22939624
24234451
25348397
|
physical association |
luminescence based mammalian interactome mapping |
ComPPI,IntAct |
| UBE2L3 |
HERC6 |
25348397
|
N/A |
physical interaction |
ComPPI |
| HSP90AA1 |
HERC6 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBQLN2 |
HERC6 |
25348397
|
N/A |
physical interaction |
ComPPI |
| UBE2L6 |
HERC6 |
25348397
|
N/A |
physical interaction |
ComPPI |
| FUS |
HERC6 |
25348397
|
N/A |
physical interaction |
ComPPI |
| NME2 |
HERC6 |
25348397
|
N/A |
physical interaction |
ComPPI |
| HERC3 |
HERC6 |
14525934
18535780
25348397
|
N/A |
experimental interaction detection,physical interaction,in vivo |
ComPPI,HPRD |
| HERC6 |
HERC4 |
14525934
18535780
25348397
|
N/A |
experimental interaction detection,physical interaction,in vivo |
ComPPI,HPRD |
| HERC6 |
HSP90AA2P |
25348397
|
N/A |
physical interaction |
ComPPI |
Visualization
