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GENE：HSD3B7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HSD3B7
FullNmae hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18324
EnsembleID ENSG00000099377
Uniprot Q9H2F3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HSD3B7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HSD3B7 GO:0003854,GO:0003854,GO:0005515,GO:0005789,GO:0005811,GO:0006699,GO:0016616,GO:0035754,GO:0047016

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HSD3B7 hsa:80270 path:hsa00120 Primary bile acid biosynthesis - Homo sapiens (human)
HSD3B7 hsa:80270 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CTCF HSD3B7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 HSD3B7 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000007F792 HSD3B7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001C0099 HSD3B7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 HSD3B7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C HSD3B7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075BC91 HSD3B7 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004B4B85 HSD3B7 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HOXA1 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KPNA4 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SPRY2 HSD3B7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP5-9 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP10-8 HSD3B7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GLRX3 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP2 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRTAP10-7 HSD3B7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRTAP4-2 HSD3B7 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
KRT86 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT31 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT40 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
APPBP2 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RGS17 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RBP3 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EFEMP1 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NR4A3 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
COMT HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LINGO1 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DAPP1 HSD3B7 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ICAM1 HSD3B7 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
EMG1 HSD3B7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MOV10 HSD3B7 25348397 N/A physical interaction ComPPI
PYGL HSD3B7 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HSD3B7 KRTAP10-9 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HSD3B7 KRTAP10-3 25348397 N/A physical interaction ComPPI
HSD3B7 TRIM42 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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