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GENE：GIGYF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GIGYF2
FullNmae GRB10 interacting GYF protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11960
EnsembleID ENSG00000204120
Uniprot Q6Y7W6

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GIGYF2 parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
GIGYF2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GIGYF2 GO:0003723,GO:0005515,GO:0005768,GO:0005783,GO:0005794,GO:0005829,GO:0005829,GO:0007631,GO:0008344,GO:0009791,GO:0010494,GO:0016020,GO:0016020,GO:0016441,GO:0017148,GO:0021522,GO:0031571,GO:0031982,GO:0032991,GO:0035264,GO:0043204,GO:0043204,GO:0045296,GO:0045947,GO:0048009,GO:0048009,GO:0048873,GO:0050881,GO:0050885,GO:0060090,GO:0060339,GO:0061157,GO:0070064,GO:0072344,GO:1990635,GO:1990635

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GIGYF2 UBB 23180781 24816145 ubiquitination reaction deubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
AR GIGYF2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 GIGYF2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 GIGYF2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 GIGYF2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 GIGYF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GIGYF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GIGYF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GIGYF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 GIGYF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GIGYF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 GIGYF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GIGYF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GIGYF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 GIGYF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 GIGYF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR GIGYF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 GIGYF2 21566225 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000AD002 GIGYF2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000017EA6A GIGYF2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000284586 GIGYF2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 GIGYF2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 GIGYF2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A GIGYF2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00001925C1 GIGYF2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB35 GIGYF2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 GIGYF2 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 GIGYF2 22135298 phosphorylation N/A PhosphoSite
CDK2 GIGYF2 22135298 phosphorylation N/A PhosphoSite
GRB10 GIGYF2 25361965 interaction type N/A PTMCode2
GIGYF2 GRB10 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNRPC GIGYF2 16120600 24234451 25348397 physical association two hybrid ComPPI,IntAct
SNRPB GIGYF2 14525934 16120600 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
CDKN1A GIGYF2 25348397 N/A physical interaction ComPPI
EMD GIGYF2 25348397 N/A physical interaction ComPPI
VCP GIGYF2 25348397 N/A physical interaction ComPPI
BMI1 GIGYF2 25348397 N/A physical interaction ComPPI
KEAP1 GIGYF2 25348397 N/A physical interaction ComPPI
WDR83 GIGYF2 25348397 N/A physical interaction ComPPI
MCM2 GIGYF2 25348397 N/A physical interaction ComPPI
SMN1 GIGYF2 25348397 N/A physical interaction ComPPI
CBY1 GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DDX20 GIGYF2 25348397 N/A physical interaction ComPPI
TIAM1 GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GRB10 GIGYF2 12771153 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
HDAC4 GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RTKN GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF1 GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
U2AF2 GIGYF2 25348397 N/A physical interaction ComPPI
YWHAB GIGYF2 24234451 24255178 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAZ GIGYF2 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
WBP11 GIGYF2 14525934 16120600 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
HSP90AA1 GIGYF2 21360678 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 GIGYF2 25348397 N/A physical interaction ComPPI
APC GIGYF2 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
CDH1 GIGYF2 25348397 N/A physical interaction ComPPI
YBX1 GIGYF2 25348397 N/A physical interaction ComPPI
MAGI1 GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MYC GIGYF2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
PHLDB2 GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PABPC1 GIGYF2 25348397 N/A physical interaction ComPPI
XPO1 GIGYF2 25348397 N/A physical interaction ComPPI
HUWE1 GIGYF2 25348397 N/A physical interaction ComPPI
EGFR GIGYF2 25348397 N/A physical interaction ComPPI
SH3PXD2A GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TUBGCP3 GIGYF2 25348397 N/A physical interaction ComPPI
PTPN13 GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
USP11 GIGYF2 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FXR1 GIGYF2 25348397 N/A physical interaction ComPPI
PRPF6 GIGYF2 25348397 N/A physical interaction ComPPI
RFX5 GIGYF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AIRE GIGYF2 25348397 N/A physical interaction ComPPI
TRIM25 GIGYF2 25348397 N/A physical interaction ComPPI
ELAVL1 GIGYF2 25348397 N/A physical interaction ComPPI
CGN GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KIF13B GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF4A2 GIGYF2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
CDC25C GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KIF1C GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TESK2 GIGYF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 RBM12 14525934 16120600 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
GIGYF2 PRPF8 25348397 N/A physical interaction ComPPI
GIGYF2 GEMIN4 25348397 N/A physical interaction ComPPI
GIGYF2 U2AF1L4 25348397 N/A physical interaction ComPPI
GIGYF2 SF3B2 25348397 N/A physical interaction ComPPI
GIGYF2 ATN1 25348397 N/A physical interaction ComPPI
GIGYF2 TNRC6B 25348397 N/A physical interaction ComPPI
GIGYF2 AGO2 25348397 N/A physical interaction ComPPI
GIGYF2 G3BP1 25348397 N/A physical interaction ComPPI
GIGYF2 CAPRIN1 25348397 N/A physical interaction ComPPI
GIGYF2 PCK1 25348397 N/A physical interaction ComPPI
GIGYF2 SIRT7 25348397 N/A physical interaction ComPPI
GIGYF2 DIS3L 20531386 24234451 25348397 26496610 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GIGYF2 HSP90AA2P 25348397 N/A physical interaction ComPPI
GIGYF2 EIF4E2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 ZNF598 25348397 N/A physical interaction ComPPI
GIGYF2 CNOT9 25348397 N/A physical interaction ComPPI
GIGYF2 TARDBP 25348397 N/A physical interaction ComPPI
GIGYF2 LGR4 25348397 N/A physical interaction ComPPI
GIGYF2 AURKB 25348397 N/A physical interaction ComPPI
GIGYF2 CEP250 25348397 N/A physical interaction ComPPI
GIGYF2 CEP57 25348397 N/A physical interaction ComPPI
GIGYF2 CEP76 25348397 N/A physical interaction ComPPI
GIGYF2 LGALS3BP 25348397 N/A physical interaction ComPPI
GIGYF2 MAGED2 25348397 N/A physical interaction ComPPI
GIGYF2 TP53 25348397 N/A physical interaction ComPPI
GIGYF2 CCDC8 25348397 N/A physical interaction ComPPI
GIGYF2 EXOSC7 25348397 N/A physical interaction ComPPI
GIGYF2 NINL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GIGYF2 MEX3C 25348397 N/A physical interaction ComPPI
GIGYF2 MRPL12 25348397 N/A physical interaction ComPPI
GIGYF2 SLC25A10 25348397 N/A physical interaction ComPPI
GIGYF2 NCAPH2 25348397 N/A physical interaction ComPPI
GIGYF2 KCTD3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 ZBTB21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 KSR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 RALGPS2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 MAST3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 LRFN1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 DENND1A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 PPM1H 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 DENND4C 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 SRGAP2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 NF1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 LPIN3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 SIPA1L1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 CAMSAP2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 NADK 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 LIMA1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 DCLK1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 RASAL2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 ZNF638 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 SH3RF3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 OSBPL6 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 MAP3K21 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 MAPKAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 PLEKHA7 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 TANC2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 NAV1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 INPP5E 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIGYF2 SNRPN 16120600 24234451 25348397 physical association two hybrid ComPPI,IntAct
GIGYF2 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
GIGYF2 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
GIGYF2 NBEAL2 24234451 25348397 29187380 association tandem affinity purification ComPPI,IntAct
PAAT GIGYF2 25348397 N/A physical interaction ComPPI
DICER1 GIGYF2 21858095 24234451 association anti tag coimmunoprecipitation IntAct
TANK GIGYF2 24234451 30561431 association virotrap IntAct
CD46 GIGYF2 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS00008BB42E GIGYF2 27087310 direct interaction,inhibition N/A NPInter
URS00009AFC01 GIGYF2 27087310 direct interaction,inhibition N/A NPInter

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