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GENE：HSPBP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HSPBP1
FullNmae HSPA (Hsp70) binding protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24989
EnsembleID ENSG00000133265
Uniprot Q9NZL4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HSPBP1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HSPBP1 GO:0000774,GO:0004857,GO:0005515,GO:0005615,GO:0005783,GO:0006457,GO:0031398,GO:0031625,GO:0032436,GO:0140313

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HSPBP1 hsa:23640 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
HSPA1A HSPBP1 21247889 23180781 physical association affinity chromatography technology InnateDB
APP HSPBP1 21832049 23180781 physical association protein array InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 HSPBP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA HSPBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HSPBP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE HSPBP1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
HSPBP1 HSPA9 25361965 interaction type N/A PTMCode2
HSPA9 HSPBP1 25361965 interaction type N/A PTMCode2
HSPBP1 HSPA1B 25361965 interaction type N/A PTMCode2
HSPA1B HSPBP1 25361965 interaction type N/A PTMCode2
HSPBP1 HSPA1A 25361965 interaction type N/A PTMCode2
HSPA1A HSPBP1 25361965 interaction type N/A PTMCode2
HSPA8 HSPBP1 25361965 interaction type N/A PTMCode2
HSPBP1 HSPA8 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SF3A3 HSPBP1 25348397 N/A physical interaction ComPPI
HSPA8 HSPBP1 14525934 16169070 16189514 19659607 24234451 25348397 25416956 29568061 9830037 association,physical association two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo,two hybrid prey pooling approach,proximity-dependent biotin identification,validated two hybrid ComPPI,HPRD,IntAct
HSPA2 HSPBP1 14525934 16189514 16713569 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
UBXN2B HSPBP1 25348397 N/A physical interaction ComPPI
QRICH1 HSPBP1 25348397 N/A physical interaction ComPPI
SH3GLB1 HSPBP1 25348397 N/A physical interaction ComPPI
GMNN HSPBP1 25348397 N/A physical interaction ComPPI
EFEMP2 HSPBP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSPBP1 HSPA1A 14525934 15694338 16713569 24234451 25348397 9830037 N/A two hybrid,experimental interaction detection,x-ray crystallography,physical interaction,two hybrid ComPPI,HPRD,IntAct
HSPBP1 HSPA1B 25348397 N/A two hybrid,x-ray crystallography,physical interaction ComPPI
HSPBP1 LRIF1 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
HSPBP1 HSPA4 14525934 19659607 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HSPBP1 HSPA9 14525934 19659607 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HSPBP1 HSPA5 14525934 19659607 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
HSPBP1 STUB1 25348397 N/A physical interaction ComPPI
HSPBP1 CRK 25348397 N/A physical interaction ComPPI
HSPBP1 PGLYRP1 21247889 25348397 27898060 N/A physical interaction ComPPI,OmniPath
HSPBP1 APP 25348397 N/A physical interaction ComPPI
HSPBP1 METTL21A 25348397 N/A physical interaction ComPPI
HSPBP1 ACTR2 25348397 N/A physical interaction ComPPI
HSPBP1 AGFG1 25348397 N/A physical interaction ComPPI
HSPBP1 ALAD 25348397 N/A physical interaction ComPPI
HSPBP1 GON7 25348397 N/A physical interaction ComPPI
HSPBP1 DBNL 25348397 N/A physical interaction ComPPI
HSPBP1 DRAP1 25348397 N/A physical interaction ComPPI
HSPBP1 ERO1A 25348397 N/A physical interaction ComPPI
HSPBP1 FKBP10 25348397 N/A physical interaction ComPPI
HSPBP1 GPN1 25348397 N/A physical interaction ComPPI
HSPBP1 P3H1 25348397 N/A physical interaction ComPPI
HSPBP1 LPP 25348397 N/A physical interaction ComPPI
HSPBP1 LRSAM1 25348397 N/A physical interaction ComPPI
HSPBP1 PPME1 25348397 N/A physical interaction ComPPI
HSPBP1 PPP1R7 25348397 N/A physical interaction ComPPI
HSPBP1 SURF2 25348397 N/A physical interaction ComPPI
HSPBP1 TPRKB 25348397 N/A physical interaction ComPPI
HSPBP1 OGT 25348397 N/A physical interaction ComPPI
HSPBP1 TOM1L1 25348397 N/A physical interaction ComPPI
HSPBP1 WDR4 25348397 N/A physical interaction ComPPI
HSPBP1 ZPR1 25348397 N/A physical interaction ComPPI
HSPBP1 FKBP8 24234451 25036637 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSPBP1 HSF1 24234451 25036637 25348397 27173435 association,physical association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
HSPBP1 NOTCH2NLA 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HSPBP1 HSPA6 25348397 N/A physical interaction ComPPI
HSPBP1 EDRF1 25348397 N/A physical interaction ComPPI
HSPBP1 NT5C2 25348397 N/A physical interaction ComPPI
HSPBP1 ELF2 25348397 N/A physical interaction ComPPI
HSPBP1 ASNS 25348397 N/A physical interaction ComPPI
HSPBP1 CSTF1 25348397 N/A physical interaction ComPPI
HSPBP1 FASN 25348397 N/A physical interaction ComPPI
HSPBP1 GARS1 25348397 N/A physical interaction ComPPI
HSPBP1 HNRNPL 25348397 N/A physical interaction ComPPI
HSPBP1 NUP50 25348397 N/A physical interaction ComPPI
HSPBP1 NMD3 25348397 N/A physical interaction ComPPI
HSPBP1 NTRK1 25348397 N/A physical interaction ComPPI
HSPBP1 MED4 25348397 N/A physical interaction ComPPI
HSPBP1 CLK1 25348397 N/A physical interaction ComPPI
HSPBP1 EVC2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
HSPBP1 CDC25C 25348397 N/A physical interaction ComPPI
HSPBP1 FAN1 25348397 N/A physical interaction ComPPI
HSPBP1 ELF1 25348397 N/A physical interaction ComPPI
HSPBP1 ARMC1 25348397 N/A physical interaction ComPPI
HSPBP1 ILRUN 25348397 N/A physical interaction ComPPI
HSPBP1 ABL2 25348397 N/A physical interaction ComPPI
HSPBP1 CCDC117 25348397 N/A physical interaction ComPPI
HSPBP1 CLTCL1 25348397 N/A physical interaction ComPPI
HSPBP1 HSF2 25348397 N/A physical interaction ComPPI
HSPBP1 ZNF703 25348397 N/A physical interaction ComPPI
HSPBP1 GAK 25348397 N/A physical interaction ComPPI
HSPBP1 CFAP298 25348397 N/A physical interaction ComPPI
HSPBP1 TACC3 25348397 N/A physical interaction ComPPI
HSPBP1 FLYWCH2 25348397 N/A physical interaction ComPPI
HSPBP1 UBAP2 25348397 N/A physical interaction ComPPI
HSPBP1 DNAJC13 25348397 N/A physical interaction ComPPI
HSPBP1 HGS 25348397 N/A physical interaction ComPPI
HSPBP1 FOXC1 25348397 N/A physical interaction ComPPI
HSPBP1 SF1 25348397 N/A physical interaction ComPPI
HSPBP1 MAP3K7 25348397 N/A physical interaction ComPPI
HSPBP1 TAB1 25348397 N/A physical interaction ComPPI
HSPBP1 ESS2 25348397 N/A physical interaction ComPPI
HSPBP1 DPH2 25348397 N/A physical interaction ComPPI
HSPBP1 QSER1 25348397 N/A physical interaction ComPPI
HSPBP1 RUFY1 25348397 N/A physical interaction ComPPI
HSPBP1 ARFIP1 25348397 N/A physical interaction ComPPI
HSPBP1 NEDD1 25348397 N/A physical interaction ComPPI
HSPBP1 ZNF503 25348397 N/A physical interaction ComPPI
HSPBP1 HMCES 25348397 N/A physical interaction ComPPI
HSPBP1 MKLN1 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
HSPBP1 EDEM3 25348397 N/A physical interaction ComPPI
HSPBP1 FBXL13 25348397 N/A physical interaction ComPPI
HSPBP1 MAP3K1 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
HSPBP1 RIF1 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
HSPBP1 TNFRSF14 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HSPBP1 WIPI2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HSPBP1 TUBB3 24234451 25348397 27291054 association pull down ComPPI,IntAct
HSPBP1 DDIT4L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSPBP1 KRT27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSPBP1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
HSPBP1 TUBG1 24234451 25348397 29568061 association pull down ComPPI,IntAct
METTL3 HSPBP1 24234451 29507755 association anti tag coimmunoprecipitation IntAct

Visualization










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