Gene Information gene info

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GENE：KLHL8

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KLHL8
FullNmae kelch like family member 8
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18644
EnsembleID ENSG00000145332
Uniprot Q9P2G9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KLHL8 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KLHL8 GO:0005654,GO:0006511,GO:0016567,GO:0016567,GO:0031463

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CUL3 KLHL8 21145461 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 KLHL8 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 KLHL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KLHL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KLHL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 KLHL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KLHL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 KLHL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS KLHL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KLHL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 KLHL8 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 KLHL8 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 KLHL8 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00003D5391 KLHL8 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000170CF4 KLHL8 23622248 25416803 26701625 mrna cleavage,inhibition clip,clash TarBase
URS00004CCA62 KLHL8 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 KLHL8 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001EB9FC KLHL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000153377 KLHL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000070CD2 KLHL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000346991 KLHL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000027080C KLHL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000041E949 KLHL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000508C13 KLHL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003883FE KLHL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000037D7E5 KLHL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000045E0EC KLHL8 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004B83FE KLHL8 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
COIL KLHL8 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SNRPF KLHL8 25348397 N/A physical interaction ComPPI
ATXN1 KLHL8 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
BMI1 KLHL8 25348397 N/A physical interaction ComPPI
DCUN1D1 KLHL8 25348397 N/A physical interaction ComPPI
SERPINF1 KLHL8 25348397 N/A physical interaction ComPPI
RACGAP1 KLHL8 25348397 N/A physical interaction ComPPI
SNRNP70 KLHL8 25348397 N/A physical interaction ComPPI
COPS5 KLHL8 25348397 N/A physical interaction ComPPI
USP7 KLHL8 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CUL3 KLHL8 25348397 N/A physical interaction ComPPI
CCT7 KLHL8 25348397 N/A physical interaction ComPPI
RAPSN KLHL8 25348397 N/A physical interaction ComPPI
COPS6 KLHL8 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TAF15 KLHL8 25348397 N/A physical interaction ComPPI
ELAVL1 KLHL8 25348397 N/A physical interaction ComPPI
KLHL8 CCDC120 25348397 N/A physical interaction ComPPI
KLHL8 GEMIN8 25348397 N/A physical interaction ComPPI
KLHL8 CCT3 25348397 N/A physical interaction ComPPI
KLHL8 UBA5 25348397 N/A physical interaction ComPPI
SIGLEC5 KLHL8 25348397 N/A physical interaction ComPPI
LGALS7 KLHL8 25348397 N/A physical interaction ComPPI

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