Gene Information gene info

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GENE：LRR1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LRR1
FullNmae leucine rich repeat protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19742
EnsembleID ENSG00000165501
Uniprot Q96L50

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LRR1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LRR1 GO:0005515,GO:0005634,GO:0005829,GO:0007165,GO:0016567

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LRR1 CUL2 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
LRR1 RBX1 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
LRR1 ELOC 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
LRR1 ELOB 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
CUL3 LRR1 21145461 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 LRR1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 LRR1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 LRR1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
NR1I2 LRR1 19129222 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 LRR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 LRR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AA464 LRR1 20304954 25416803 mrna cleavage,inhibition array technology TarBase
URS00000BE495 LRR1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CUL5 LRR1 25348397 N/A physical interaction ComPPI
RELL2 LRR1 25348397 N/A physical interaction ComPPI
CDKN1A LRR1 25348397 N/A physical interaction ComPPI
UBE2D1 LRR1 25348397 N/A physical interaction ComPPI
PNMA2 LRR1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
COPS5 LRR1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COP1 LRR1 25348397 N/A physical interaction ComPPI
RBX1 LRR1 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL3 LRR1 25348397 N/A physical interaction ComPPI
COPS2 LRR1 25348397 N/A physical interaction ComPPI
CUL2 LRR1 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS3 LRR1 25348397 N/A physical interaction ComPPI
COPS4 LRR1 25348397 N/A physical interaction ComPPI
COPS6 LRR1 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS7A LRR1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS8 LRR1 25348397 N/A physical interaction ComPPI
ELOB LRR1 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELOC LRR1 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TNFRSF9 LRR1 11804328 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
COPS7B LRR1 25348397 N/A physical interaction ComPPI
LRR1 PTPN14 25348397 N/A physical interaction ComPPI
LRR1 BTBD1 25348397 N/A physical interaction ComPPI
LRR1 TRIP13 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LRR1 MTUS2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LRR1 ZBTB38 25348397 N/A physical interaction ComPPI
LRR1 RAB5C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LRR1 RAPGEF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LRR1 PFKFB4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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