Gene Information gene info

GENE:MED10

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MED10
FullNmae mediator complex subunit 10
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28760
EnsembleID ENSG00000133398
Uniprot Q9BTT4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MED10 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MED10 GO:0000151,GO:0003712,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0016567,GO:0016592,GO:0032968,GO:0045944,GO:0051123,GO:0060261,GO:0061630,GO:0070847

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MED10 IRF1 15893730 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 MED10 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 MED10 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MED10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 MED10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MED10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MED10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MED10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MED10 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 MED10 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000027080C MED10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000019F055 MED10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001597DC MED10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000610EFA MED10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD MED10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000052E1A6 MED10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF MED10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 MED10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000081E1F MED10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 MED10 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE MED10 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ARHGDIG MED10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
POLR2L MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NPM1 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TP53BP1 MED10 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
MED21 MED10 14576168 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED8 MED10 12149480 12584197 14576168 14638676 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
FBXW7 MED10 25348397 N/A physical interaction ComPPI
TRIP4 MED10 25348397 N/A physical interaction ComPPI
RBM39 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
NONO MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TTN MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MED1 MED10 14576168 14638676 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED24 MED10 14576168 15175163 17404243 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
UBB MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PEBP1 MED10 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
EEF1A1 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MED22 MED10 12584197 14576168 14638676 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED30 MED10 14576168 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED9 MED10 14638676 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED11 MED10 12584197 14576168 14638676 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED23 MED10 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
POLR2E MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2A MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HDAC6 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
HNF4A MED10 25348397 N/A physical interaction ComPPI
MED17 MED10 12149480 12584197 14576168 14638676 15175163 17404243 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED28 MED10 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED25 MED10 14576168 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction ComPPI,IntAct
DDX3X MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MED14 MED10 14576168 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED12 MED10 14576168 15175163 17404243 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDK8 MED10 15175163 23602568 24234451 25348397 26496610 29568061 association anti tag coimmunoprecipitation,pull down,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
MED26 MED10 14576168 15175163 17404243 21729782 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED13 MED10 14576168 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
QKI MED10 25348397 N/A physical interaction ComPPI
PTBP1 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BIRC5 MED10 25348397 N/A physical interaction ComPPI
ESR1 MED10 25348397 N/A physical interaction ComPPI
ESR2 MED10 25348397 N/A physical interaction ComPPI
RECQL5 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
CCAR1 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MED6 MED10 12584197 14576168 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED15 MED10 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
POLR2K MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2J MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MOB4 MED10 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
AFF4 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EPAS1 MED10 25348397 N/A physical interaction ComPPI
EIF4A1 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MED31 MED10 14576168 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
CDK19 MED10 15175163 23602568 24234451 25348397 association,physical association anti tag coimmunoprecipitation,physical interaction,ion exchange chromatography,tandem affinity purification ComPPI,IntAct
POLR2F MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2C MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2G MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED27 MED10 14576168 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
TARDBP MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MED16 MED10 14576168 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED20 MED10 14576168 15175163 17404243 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED19 MED10 12584197 14576168 14638676 15175163 21729782 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED13L MED10 14576168 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2D MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED18 MED10 12584197 14576168 14638676 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
ELL2 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MED4 MED10 14576168 14638676 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
POLR2H MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2B MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2I MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CCNC MED10 15175163 17404243 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NAP1L1 MED10 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KANSL3 MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TCL1B MED10 25348397 N/A physical interaction ComPPI
MED10 KDM4B 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MED10 MED29 14576168 14638676 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED10 HSPA1L 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MED10 FUCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MED7 MED10 14576168 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
TMLHE MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MED10 TSH 25348397 N/A anti tag coimmunoprecipitation ComPPI
MED10 MED10 14576168 15175163 24234451 association anti tag coimmunoprecipitation IntAct

Visualization