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GENE：METAP1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol METAP1
FullNmae methionyl aminopeptidase 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15789
EnsembleID ENSG00000164024
Uniprot P53582

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
METAP1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
METAP1 GO:0004177,GO:0004177,GO:0004239,GO:0005515,GO:0005737,GO:0005829,GO:0005829,GO:0006417,GO:0006508,GO:0008235,GO:0018206,GO:0031365,GO:0046872,GO:0051604,GO:0070006,GO:0070527

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR METAP1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 METAP1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 METAP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 METAP1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 METAP1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 METAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA METAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF METAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 METAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 METAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 METAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 METAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 METAP1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EED18 METAP1 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000D2680 METAP1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000008A99 METAP1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000122F23 METAP1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ZMAT2 METAP1 25348397 N/A physical interaction ComPPI
GLRX3 METAP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SMAD9 METAP1 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
HNRNPU METAP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EXOC3 METAP1 25348397 N/A physical interaction ComPPI
NPPA METAP1 25348397 N/A physical interaction ComPPI
TRIM25 METAP1 25348397 N/A physical interaction ComPPI
HECW2 METAP1 25348397 N/A physical interaction ComPPI
ZRANB1 METAP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RBM42 METAP1 25348397 N/A physical interaction ComPPI
INCA1 METAP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLEKHG4 METAP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GH2 METAP1 25348397 N/A physical interaction ComPPI
G3BP1 METAP1 25348397 N/A physical interaction ComPPI
NCBP3 METAP1 24234451 26382858 association pull down IntAct
METAP1 SYTL4 24234451 30021884 physical association cross-linking study IntAct

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