GENE:METTL21A
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | METTL21A |
| FullNmae | methyltransferase 21A, HSPA lysine |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:30476 |
| EnsembleID | ENSG00000144401 |
| Uniprot | Q8WXB1 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| METTL21A | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| METTL21A | GO:0005515,GO:0005654,GO:0005737,GO:0005829,GO:0006338,GO:0006479,GO:0008276,GO:0016279,GO:0016279,GO:0016279,GO:0018022,GO:0018022,GO:0030544,GO:0031072,GO:0032991,GO:0042054,GO:0051117 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | METTL21A | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | METTL21A | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | METTL21A | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | METTL21A | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | METTL21A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | METTL21A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | METTL21A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | METTL21A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | METTL21A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | METTL21A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | METTL21A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | METTL21A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | METTL21A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS000021D7C8 | METTL21A | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001A6D0C | METTL21A | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005D4F5 | METTL21A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007A060 | METTL21A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000136174 | METTL21A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002C02E4 | METTL21A | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000011A030 | METTL21A | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000077DDE | METTL21A | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000383DF4 | METTL21A | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D814 | METTL21A | 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000EE7F0 | METTL21A | 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000030F801 | METTL21A | 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000011DF | METTL21A | 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00002ED720 | METTL21A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B0B46 | METTL21A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000076E54 | METTL21A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018D2BE | METTL21A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FD1A | METTL21A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000021D08 | METTL21A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000025EABA | METTL21A | 23313552 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000079D48 | METTL21A | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000170D8B | METTL21A | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000411752 | METTL21A | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041E780 | METTL21A | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HSPA8 | METTL21A | 25348397 | N/A | physical interaction | ComPPI |
| BAG3 | METTL21A | 25348397 | N/A | physical interaction | ComPPI |
| HSPBP1 | METTL21A | 25348397 | N/A | physical interaction | ComPPI |
| HSPA5 | METTL21A | 25348397 | N/A | physical interaction | ComPPI |
| HSPA1A | METTL21A | 25348397 | N/A | physical interaction | ComPPI |
| HSPA1B | METTL21A | 25348397 | N/A | physical interaction | ComPPI |
| SDCBP | METTL21A | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| HSPA4 | METTL21A | 25348397 | N/A | physical interaction | ComPPI |
| PFDN5 | METTL21A | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| HSPH1 | METTL21A | 25348397 | N/A | physical interaction | ComPPI |
| HSPA9 | METTL21A | 25348397 | N/A | physical interaction | ComPPI |
| DYNC1H1 | METTL21A | 25348397 | N/A | physical interaction | ComPPI |
| ZRANB1 | METTL21A | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| LNX1 | METTL21A | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| ARPC4 | METTL21A | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| CCDC88A | METTL21A | 25348397 | N/A | physical interaction | ComPPI |
| ATRIP | METTL21A | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| HSPA1L | METTL21A | 25348397 | N/A | physical interaction | ComPPI |
