Gene Information gene info

GENE:MFNG

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MFNG
FullNmae MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7038
EnsembleID ENSG00000100060
Uniprot O00587

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MFNG immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MFNG GO:0000139,GO:0001825,GO:0002315,GO:0005615,GO:0007389,GO:0008593,GO:0008593,GO:0033829,GO:0033829,GO:0045747,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MFNG hsa:4242 path:hsa00514 Other types of O-glycan biosynthesis - Homo sapiens (human)
MFNG hsa:4242 path:hsa04330 Notch signaling pathway - Homo sapiens (human)
MFNG hsa:4242 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MFNG DLL3 15574878 23331499 stimulation N/A SignaLink
MFNG JAG1 12036964 15574878 23331499 inhibition N/A SignaLink
POFUT1 MFNG 15380241 23331499 stimulation N/A SignaLink
MFNG NOTCH2 11346656 23331499 interaction type N/A SignaLink
MFNG DLL1 11346656 12036964 23331499 interaction type N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 MFNG 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 MFNG 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MFNG 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MYC MFNG N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 MFNG 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
NOTCH1 MFNG 10935626 12486116 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
DLL1 MFNG 12036964 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MFNG NOTCH2 11346656 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MFNG JAG1 12036964 14525934 N/A experimental interaction detection HPRD
MFNG NOTCH1 10935626 12486116 27898060 stimulant N/A OmniPath
MFNG NOTCH2 11346656 27898060 stimulant N/A OmniPath

Visualization