GENE：MFSD6
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MFSD6 |
| FullNmae | major facilitator superfamily domain containing 6 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:24711 |
| EnsembleID | ENSG00000151690 |
| Uniprot | Q6ZSS7 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MFSD6 | pyroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| MFSD6 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MFSD6 | GO:0005515,GO:0005886,GO:0016020,GO:0042590 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | MFSD6 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| E2F4 | MFSD6 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | MFSD6 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | MFSD6 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | MFSD6 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | MFSD6 | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | MFSD6 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | MFSD6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | MFSD6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | MFSD6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | MFSD6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | MFSD6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | MFSD6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | MFSD6 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | MFSD6 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS00002C0FCB | MFSD6 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000006FDD4 | MFSD6 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D860 | MFSD6 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002E92A8 | MFSD6 | 20371350 21572407 23446348 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000009265 | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000058863C | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AAA0 | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000050CCE0 | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001EFBE3 | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003E1A9 | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000939AF | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000052EA98 | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000166778 | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00005FDCD1 | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CF1D2 | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040FA88 | MFSD6 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000077DDE | MFSD6 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005481D | MFSD6 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000011DF | MFSD6 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ADIPOQ | MFSD6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBE2N | MFSD6 | 24234451 25260751 25348397 | ubiquitination reaction | ubiquitinase assay | ComPPI,IntAct |
| LY6E | MFSD6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| EBP | MFSD6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBA1 | MFSD6 | 24234451 25260751 25348397 | ubiquitination reaction | ubiquitinase assay | ComPPI,IntAct |
| CD79A | MFSD6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| APH1A | MFSD6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| UBE2V1 | MFSD6 | 24234451 25260751 25348397 | ubiquitination reaction | ubiquitinase assay | ComPPI,IntAct |
| GJB2 | MFSD6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| PDCD1LG2 | MFSD6 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |