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GENE：MOCOS

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MOCOS
FullNmae molybdenum cofactor sulfurase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:18234
EnsembleID ENSG00000075643
Uniprot Q96EN8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MOCOS immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MOCOS GO:0005515,GO:0005575,GO:0005829,GO:0006777,GO:0008265,GO:0008265,GO:0008265,GO:0016829,GO:0030151,GO:0030170,GO:0032324,GO:0043545,GO:0043545,GO:0102867

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MOCOS hsa:55034 path:hsa00790 Folate biosynthesis - Homo sapiens (human)
MOCOS hsa:55034 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA1 MOCOS 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 MOCOS 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 MOCOS 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 MOCOS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MOCOS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MOCOS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MOCOS 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MOCOS 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 MOCOS 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00001CE046 MOCOS 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000076E54 MOCOS 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 MOCOS 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A MOCOS 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000058276F MOCOS 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 MOCOS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E MOCOS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F31F4 MOCOS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002971AB MOCOS 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00007455B8 MOCOS 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
MOCOS APOA1 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MOCOS TSHR 25348397 N/A physical interaction ComPPI
MOCOS HDAC7 25348397 N/A physical interaction ComPPI
MOCOS PLAU 25348397 N/A physical interaction ComPPI
MOCOS SEPTIN8 25348397 N/A physical interaction ComPPI
MOCOS XPO1 25348397 N/A physical interaction ComPPI
MOCOS CNTROB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MOCOS RGS20 25348397 N/A physical interaction ComPPI
MOCOS IRF3 25348397 N/A physical interaction ComPPI
MOCOS TKT 25348397 N/A physical interaction ComPPI
MOCOS DNAJC7 25348397 N/A physical interaction ComPPI
MOCOS CRTAC1 25348397 N/A physical interaction ComPPI
MOCOS HNRNPL 25348397 N/A physical interaction ComPPI
MOCOS PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct

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